Iron oxide nanoparticles in regenerative medicine and tissue engineering

RP Friedrich, I Cicha, C Alexiou - Nanomaterials, 2021 - mdpi.com
In recent years, many promising nanotechnological approaches to biomedical research
have been developed in order to increase implementation of regenerative medicine and …

Nanomaterial-mediated autophagy: Coexisting hazard and health benefits in biomedicine

X Feng, Y Zhang, C Zhang, X Lai, Y Zhang… - Particle and fibre …, 2020 - Springer
Background Widespread biomedical applications of nanomaterials (NMs) bring about
increased human exposure risk due to their unique physicochemical properties. Autophagy …

Inner ear drug delivery: recent advances, challenges, and perspective

J Hao, SK Li - European Journal of Pharmaceutical Sciences, 2019 - Elsevier
Effective and safe treatment of auditory and vestibular diseases has become increasingly
dependent on inner ear drug delivery systems. This review highlights recent advances in …

Adsorption of doxorubicin hydrochloride on glutaric anhydride functionalized Fe3O4@ SiO2 magnetic nanoparticles

W Cai, M Guo, X Weng, W Zhang, Z Chen - Materials Science and …, 2019 - Elsevier
Since Fe 3 O 4 nanoparticles synthesized by plant extracts possess good bio-compatibility
and superparamagnetic properties, the possibility of these could be used as a carrier in drug …

Nanocarriers for drug delivery to the inner ear: Physicochemical key parameters, biodistribution, safety and efficacy

C Jaudoin, F Agnely, Y Nguyen, E Ferrary… - International Journal of …, 2021 - Elsevier
Despite the high incidence of inner ear disorders, there are still no dedicated medications on
the market. Drugs are currently administered by the intratympanic route, the safest way to …

MRI based on iron oxide nanoparticles contrast agents: effect of oxidation state and architecture

Y Javed, K Akhtar, H Anwar, Y Jamil - Journal of Nanoparticle Research, 2017 - Springer
Iron oxide nanoparticles (IONPs) extensively employed beyond regenerative medicines to
imaging disciplines because of their great constituents for magneto-responsive nano …

Potential nanotechnology-based diagnostic and therapeutic approaches for Meniere's disease

A Kashizadeh, C Pastras, N Rabiee… - … , Biology and Medicine, 2022 - Elsevier
Meniere's disease (MD) is a progressive inner ear disorder involving recurrent and
prolonged episodes or attacks of vertigo with associated symptoms, resulting in a …

Imaging of temporal bone

I Pyykkö, J Zou, R Gürkov, S Naganawa… - Vestibular …, 2019 - karger.com
Multidetector computed tomography has been the benchmark for visualizing bony changes
of the ear, but has recently been challenged by cone-beam computed tomography. In both …

[HTML][HTML] Developments in bio-inspired nanomaterials for therapeutic delivery to treat hearing loss

C Rathnam, STD Chueng, YLM Ying… - Frontiers in cellular …, 2019 - frontiersin.org
Sensorineural hearing loss affects millions of people worldwide and is a growing concern in
the aging population. Treatment using aminoglycoside antibiotics for infection and exposure …

Local delivery of therapeutics to the cochlea using nanoparticles and other biomaterials

S Dash, J Zuo, PS Steyger - Pharmaceuticals, 2022 - mdpi.com
Hearing loss negatively impacts the well-being of millions of people worldwide. Systemic
delivery of ototherapeutics has limited efficacy due to severe systemic side effects and the …