Phosphodiesterases (PDEs), enzymes that degrade 3′, 5′-cyclic nucleotides, are being
pursued as therapeutic targets for several diseases, including those affecting the nervous …

Reproductive biology is a uniquely important topic since it is about germ cells, which are
central for transmitting genetic information from generation to generation. In this review, we …

Fertility traits measured early in life define the reproductive potential of heifers. Knowledge of
genetics and biology can help devise genomic selection methods to improve heifer fertility …

The objective of this study was to investigate the effect of milrinone supplementation as a
phosphodiesterase 3A inhibitor during in vitro maturation (IVM) to coordinate the …

As the immature oocytes are submitted to cryopreservation, their surrounding cumulus cells
(CCs) will inevitably suffer, which may have some adverse effects on subsequent oocyte …

Increasing infertility is one of the most serious health problems of today. Over the past few
years, we have had the opportunity to follow the progress of technologies focused on the …

The oocyte quality remains as one of the major problems associated with poor in vitro
fertilization (IVF) rate and assisted reproductive technology (ART) failure worldwide. The …

Cyclic nucleotide phosphodiesterases (PDEs) are group of enzymes responsible for the
hydrolysis of cyclic adenosine 3′, 5′ monophosphate (cAMP) and cyclic guanosine 3 …

Protein- mediated enamel mineralization Page 1 307 Nitric oxide signaling during meiotic cell
cycle regulation in mammalian oocytes Meenakshi Tiwari1, Shilpa Prasad1, Ashutosh N …

In mammals, journey from metaphase‐I (M‐I) to metaphase‐II (M‐II) is important since
oocyte extrude first polar body (PB‐I) and gets converted into haploid gamete. The …