Carbapenem-resistant Pseudomonas aeruginosa (CR-PA) is a major healthcare-associated
pathogen worldwide. In the United States, 10–30% of P. aeruginosa isolates are …

Gram-negative bacteremia is a devastating public health threat, with high mortality in
vulnerable populations and significant costs to the global economy. Concerningly, rates of …

Klebsiella pneumoniae is an important multidrug-resistant (MDR) pathogen affecting
humans and a major source for hospital infections associated with high morbidity and …

Carbapenem-resistant Pseudomonas aeruginosa is one of the major concerns in clinical
settings impelling a great challenge to antimicrobial therapy for patients with infections …

Multidrug resistance is quite common among non-fermenting Gram-negative rods, in
particular among clinically relevant species including Pseudomonas aeruginosa and …

Klebsiella pneumoniae carbapenemases (KPCs) were originally identified in the USA in
1996. Since then, these versatile β-lactamases have spread internationally among Gram …

A rapid and reliable PCR-based technique was developed for detection of genes encoding
carbapenemases belonging to different classes. Primers were designed to amplify the …

Pseudomonas aeruginosa is intrinsically resistant to a variety of antimicrobials and can
develop resistance during anti-pseudomonal chemotherapy both of which compromise …

Multilocus sequence typing reveals that many bacterial species have a clonal structure and
that some clones are widespread. This underlying phylogeny was not revealed by pulsed …

Metallo-β-lactamase-producing Pseudomonas aeruginosa (MPPA) is an important
nosocomial pathogen that shows resistance to all β-lactam antibiotics except monobactams …