Ether lipids from archaeas in nano-drug delivery and vaccination
EL Romero, MJ Morilla - International Journal of Pharmaceutics, 2023 - Elsevier
Archaea are microorganisms more closely related to eukaryotes than bacteria. Almost 50
years after being defined as a new domain of life on earth, new species continue to be …
years after being defined as a new domain of life on earth, new species continue to be …
Interactions between macrophages and biofilm during Staphylococcus aureus-associated implant infection: difficulties and solutions
M Li, J Yu, G Guo, H Shen - Journal of Innate Immunity, 2023 - karger.com
Staphylococcus aureus (S. aureus) biofilm is the major cause of failure of implant infection
treatment that results in heavy social and economic burden on individuals, families, and …
treatment that results in heavy social and economic burden on individuals, families, and …
Size and charge adaptive clustered nanoparticles targeting the biofilm microenvironment for chronic lung infection management
Chronic lung infection caused by bacterial biofilms is an extremely serious clinical problem,
which can lead to the failure of antibiotic therapy. Although nanoparticles have shown great …
which can lead to the failure of antibiotic therapy. Although nanoparticles have shown great …
Advancing biofilm management through nanoformulation strategies: a review of dosage forms and administration routes
O Simsekli, I Bilinmis, S Celik, G Arık… - Journal of Drug …, 2023 - Taylor & Francis
Biofilms are complex microbial communities formed by the attachment of bacteria or fungi to
surfaces encased in a self-produced polymeric matrix. These biofilms are highly resistant to …
surfaces encased in a self-produced polymeric matrix. These biofilms are highly resistant to …
Liposomes-based drug delivery systems of anti-biofilm agents to combat bacterial biofilm formation
All currently approved antibiotics are being met by some degree of resistance by the
bacteria they target. Biofilm formation is one of the crucial enablers of bacterial resistance …
bacteria they target. Biofilm formation is one of the crucial enablers of bacterial resistance …
Hypoxia-sensitive adjuvant loaded liposomes enhance the antimicrobial activity of azithromycin via phospholipase-triggered releasing for Pseudomonas aeruginosa …
Y Rao, Y Sun, P Li, M Xu, X Chen, Y Wang… - International Journal of …, 2022 - Elsevier
Robust biofilms and the complex airway environment with thick sputum, local hypoxia and
persistent inflammation induce the intractability of chronic pulmonary infections caused by …
persistent inflammation induce the intractability of chronic pulmonary infections caused by …
Lipid-based nanomedicines for the treatment of bacterial respiratory infections: Current state and new perspectives
EM Arroyo-Urea, M Lázaro-Díez, J Garmendia… - …, 2024 - Taylor & Francis
The global threat posed by antimicrobial resistance demands urgent action and the
development of effective drugs. Lower respiratory tract infections remain the deadliest …
development of effective drugs. Lower respiratory tract infections remain the deadliest …
Doxorubicin loaded thermostable nanoarchaeosomes: a next-generation drug carrier for breast cancer therapeutics
KV Babunagappan, A Seetharaman, S Ariraman… - Nanoscale …, 2024 - pubs.rsc.org
Breast cancer has a poor prognosis due to the toxic side effects associated with high doses
of chemotherapy. Liposomal drug encapsulation has resulted in clinical success in …
of chemotherapy. Liposomal drug encapsulation has resulted in clinical success in …
Thymus vulgaris essential oil+ tobramycin within nanostructured archaeolipid carriers: A new approach against Pseudomonas aeruginosa biofilms
Background Pseudomonas aeruginosa biofilms in the respiratory tract of patients with an
excessive inflammatory context are difficult to eradicate. New medicines that simultaneously …
excessive inflammatory context are difficult to eradicate. New medicines that simultaneously …
Improved stability and biological activity of bacterioruberin in nanovesicles
AT Caimi, O Yasynska, PCR Rojas, EL Romero… - Journal of Drug Delivery …, 2022 - Elsevier
Bacterioruberin (BR) is a dipolar C50 isoprenoid with 13 conjugated double bonds and four
terminals hydroxyl groups produced by most members of the Haloferacaceae family of …
terminals hydroxyl groups produced by most members of the Haloferacaceae family of …