Overlapping protective and destructive regulatory pathways in apical periodontitis

IJ Márton, C Kiss - Journal of endodontics, 2014 - Elsevier
Introduction Protective and destructive immunoreactions take place simultaneously in apical
periodontitis. However, the same reactions defending the periapical area from infection …

MMP9 protects against LPS-induced inflammation in osteoblasts

H Zhang, L Liu, C Jiang, K Pan, J Deng… - Innate …, 2020 - journals.sagepub.com
The matrix metalloproteinase (MMP) family is widely involved in the destruction of the pulp
and apical tissues in the inflammatory process. MMP9 is closely related to oral inflammation …

Effectiveness of calcium hydroxide-based intracanal medication on infectious/inflammatory contents in teeth with post-treatment apical periodontitis

M Barbosa-Ribeiro, R Arruda-Vasconcelos… - Clinical oral …, 2019 - Springer
Objective The objective of this work was to investigate in vivo the effects of calcium
hydroxide-based intracanal medication (ICM) on the levels of bacteria, pro-inflammatory …

Genetic susceptibility to periapical disease: conditional contribution of MMP2 and MMP3 genes to the development of periapical lesions and healing response

R Menezes-Silva, S Khaliq, K Deeley, A Letra… - Journal of …, 2012 - Elsevier
INTRODUCTION: It has been proposed that individual genetic predisposition may contribute
to a persistent apical periodontitis condition. Matrix metalloproteinases (MMPs) are …

Matrix metalloproteinase expression in teeth with apical periodontitis is differentially modulated by the modality of root canal treatment

FWG Paula-Silva, LAB Da Silva, YL Kapila - Journal of Endodontics, 2010 - Elsevier
INTRODUCTION: The objective of this study was to investigate the expression of matrix
metalloproteinases (MMPs) in apical periodontitis and during the periapical healing phase …

[HTML][HTML] The Link between Periodontal Disease and Asthma: How Do These Two Diseases Affect Each Other?

H Tamiya, M Abe, T Nagase, A Mitani - Journal of Clinical Medicine, 2023 - mdpi.com
A growing body of evidence suggests that the effects of poor oral hygiene extend beyond the
oral cavity and are associated with a variety of systemic diseases, including asthma. Asthma …

[HTML][HTML] Immunolocalization of matrix metalloproteinases-2 and-9 during apical periodontitis development

MV Corotti, WF Zambuzzi, KBS Paiva, R Menezes… - Archives of Oral …, 2009 - Elsevier
OBJECTIVE: The objective of this study was to determine the expression of matrix
metalloproteinase-2 (MMP-2) and-9 (MMP-9) during apical periodontitis development …

Clinical investigation of matrix metalloproteinases, tissue inhibitors of matrix metalloproteinases, and matrix metalloproteinase/tissue inhibitors of matrix …

FC Martinho, FFC Teixeira, FGR Cardoso… - Journal of …, 2016 - Elsevier
Introduction This clinical study investigated the levels of metalloproteinases (MMPs) and
their tissue inhibitors (TIMPs) and respective forms (MMP/TIMP complexes) in apical …

[HTML][HTML] Network pharmacology combined with GEO database identifying the mechanisms and molecular targets of Polygoni Cuspidati Rhizoma on Peri-implants

C Shan, X Ji, Z Wu, J Zhao - Scientific Reports, 2022 - nature.com
Peri-implants is a chronic disease leads to the bone resorption and loss of implants.
Polygoni Cuspidati Rhizoma (PCRER), a traditional Chinese herbal has been used to treat …

Association between bacteria occurring in the apical canal system and expression of bone‐resorbing mediators and matrix metalloproteinases in apical periodontitis

A Takahama Jr, IN Rôças, ISP Faustino… - International …, 2018 - Wiley Online Library
Aim To evaluate the association between the presence of selected bacterial species/groups
in the apical root canal and expression of mediators of soft and bone tissue destruction in …