Uncovering the Hidden Credentials of Brucella Virulence

RM Roop, IS Barton, D Hopersberger… - … and Molecular Biology …, 2021 - Am Soc Microbiol
Bacteria in the genus Brucella are important human and veterinary pathogens. The abortion
and infertility they cause in food animals produce economic hardships in areas where the …

Mechanisms of nickel toxicity in microorganisms

L Macomber, RP Hausinger - Metallomics, 2011 - academic.oup.com
Nickel has long been known to be an important human toxicant, including having the ability
to form carcinomas, but until recently nickel was believed to be an issue only to …

Nickel uptake and utilization by microorganisms

SB Mulrooney, RP Hausinger - FEMS microbiology reviews, 2003 - academic.oup.com
Nickel is an essential nutrient for selected microorganisms where it participates in a variety
of cellular processes. Many microbes are capable of sensing cellular nickel ion …

The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts

IT Paulsen, R Seshadri, KE Nelson… - Proceedings of the …, 2002 - National Acad Sciences
The 3.31-Mb genome sequence of the intracellular pathogen and potential bioterrorism
agent, Brucella suis, was determined. Comparison of B. suis with Brucella melitensis has …

Comparative and functional genomic analysis of prokaryotic nickel and cobalt uptake transporters: evidence for a novel group of ATP-binding cassette transporters

DA Rodionov, P Hebbeln, MS Gelfand… - Journal of …, 2006 - Am Soc Microbiol
The transition metals nickel and cobalt, essential components of many enzymes, are taken
up by specific transport systems of several different types. We integrated in silico and in vivo …

The Brucella suis virB operon is induced intracellularly in macrophages

ML Boschiroli, S Ouahrani-Bettache… - Proceedings of the …, 2002 - National Acad Sciences
A type IV secretion system similar to the VirB system of the phytopathogen Agrobacterium
tumefaciens is essential for the intracellular survival and multiplication of the mammalian …

Heavy metal tolerance and metal homeostasis in Pseudomonas putida as revealed by complete genome analysis

D Cánovas, I Cases… - Environmental …, 2003 - Wiley Online Library
The genome of Pseudomonas putida KT2440 encodes an unexpected capacity to tolerate
heavy metals and metalloids. The availability of the complete chromosomal sequence …

Canonical and ECF-type ATP-binding cassette importers in prokaryotes: diversity in modular organization and cellular functions

T Eitinger, DA Rodionov, M Grote… - FEMS microbiology …, 2011 - academic.oup.com
Since their discovery in the 1960s as 'osmotic shock-sensitive'transporters, a plethora of so-
called binding protein-dependent (canonical) ATP-binding cassette (ABC) importers has …

Nickel homeostasis and nickel regulation: an overview

Y Li, DB Zamble - Chemical reviews, 2009 - ACS Publications
Nickel is an essential catalytic cofactor of enzymes found in eubacteria, archaebacteria,
fungi, and plants. 1-6 These enzymes catalyze a diverse array of reactions that include both …

Comparative phylogenomics and evolution of the Brucellae reveal a path to virulence

AR Wattam, JT Foster, SP Mane… - Journal of …, 2014 - Am Soc Microbiol
Brucella species include important zoonotic pathogens that have a substantial impact on
both agriculture and human health throughout the world. Brucellae are thought of as “stealth …