The role of hypoleptinemia in the psychological and behavioral adaptation to starvation: Implications for anorexia nervosa

J Hebebrand, T Hildebrandt, H Schlögl, J Seitz… - Neuroscience & …, 2022 - Elsevier
This narrative review aims to pinpoint mental and behavioral effects of starvation, which may
be triggered by hypoleptinemia and as such may be amenable to treatment with leptin …

[HTML][HTML] Rapid emergence of appetite and hunger resulting in weight gain and improvement of eating disorder symptomatology during and after short-term off-label …

G Gradl-Dietsch, G Milos, M Wabitsch, R Bell… - Obesity Facts, 2023 - karger.com
Off-label treatment of a 15-year-old female patient with anorexia nervosa (AN) with human
recombinant leptin (metreleptin) for nine days was associated with self-reported increments …

[HTML][HTML] Restlessness and an increased urge to move (drive for activity) in anorexia nervosa may strengthen personal motivation to maintain caloric restriction and …

RC Casper - Frontiers in Psychology, 2022 - frontiersin.org
Anorexia nervosa (AN), a disorder of voluntary food restriction leading to severe weight loss
in female adolescents, remains an enigma. In particular, the appropriation of the starved thin …

[HTML][HTML] Association of cardiovascular risk factors and lifestyle behaviors with aortic aneurysm: A Mendelian randomization study

J Zhou, J Lin, Y Zheng - Frontiers in Genetics, 2022 - frontiersin.org
Objective: To examine the causality between hypertension, diabetes, other cardiovascular
risk factors, lifestyle behaviors and the aortic aneurysm among patients of European …

The Role of Circadian Rhythms and Sleep in Anorexia Nervosa

H Wilcox, V Paz, R Saxena, JW Winkelman… - JAMA Network …, 2024 - jamanetwork.com
Importance Observational studies have associated anorexia nervosa with circadian rhythms
and sleep traits. However, the direction of causality and the extent of confounding by …

[PDF][PDF] Genetic variants identified in novel candidate genes for anorexia nervosa and analysis of molecular pathways for diagnostic applications

K Donato, MC Medori, A Macchia… - European Review for …, 2023 - europeanreview.org
OBJECTIVE: Anorexia nervosa (AN) is a severe psychiatric disorder characterized by an
intense fear of gaining weight, a relentless pursuit of thinness, and a distorted body image …

An Evolutionary Perspective on the Genetics of Anorexia Nervosa

E Breton, T Kaufmann - medRxiv, 2023 - medrxiv.org
Anorexia nervosa (AN) is a serious psychiatric disorder that typically emerges around
adolescence and predominantly affects girls and women. Recent progress has been made …

The Biology of Anorexia Nervosa: A New Narrative Overview

K Skowron, M Kurnik-Łucka, K Gil - Eating Disorders, 2022 - Springer
Anorexia nervosa, one of the most deadly mental disorders, is a pathophysiologically
complex mosaic of numerous extensively investigated pathways, and the current state of …

Genetics of Eating Disorders

HJ Watson, HL Davies, AB Palmos - Eating Disorders: An International …, 2023 - Springer
Family and twin studies have shown that eating disorders are moderately heritable. Newer
methods, such as genome-wide association studies (GWASs), are guiding molecular …

[PDF][PDF] Rapid Emergence of Appetite and Hunger Resulting in Weight Gain and Improvement of Eating Disorder Symptomatology during and after Short-Term Off-Label …

GGDGM Martin, WR Bella, FTJAJ Hebebranda - 2022 - scienceopen.com
Off-label treatment of a 15-year-old female patient with anorexia nervosa (AN) with human
recombinant leptin (metreleptin) for nine days was associated with self-reported increments …