This Perspective describes the classification, structures, substrates, mechanisms of action,
and implications of human neuraminidases (hNEUs) in various pathologies. Some inhibitors …

Mimosine [β‐[N‐(3‐hydroxy‐4‐oxypyridyl)]‐α‐aminopropionic acid] is a non‐protein amino
acid found in the members of Mimosoideae family. There are a considerable number of …

Five flavonols (3, 5, and 9–11) were isolated from Rhodiola rosea, and compared with
commercially available flavonoids (1, 2, 4, 6–8, and 12–14) to facilitate analysis of their …

The emergence of highly pathogenic influenza A virus strains, such as the new H1N1 swine
influenza (novel influenza), represents a serious threat to global human health. During our …

The emergence of drug-resistant influenza viruses and the threat of pandemics highlight the
need for new and effective antiviral agents. In this study, we describe the isolation of 3 new …

As part of an ongoing study focused on the discovery of anti-influenza agents from plants,
four new (1− 4) and 10 known (5− 14) C-methylated flavonoids were isolated from a …

We isolated 18 polyphenols with neuraminidase inhibitory activity from methanol extracts of
the roots of Glycyrrhiza uralensis. These polyphenols consisted of four chalcones (1–4), nine …

In recent decades, high-performance computing (HPC) technologies and supercomputers in
China have significantly advanced, resulting in remarkable achievements. Computational …

As part of our ongoing effort to develop influenza virus neuraminidase (NA) inhibitors from
various medicinal plants, we utilized bioassay-guided fractionation to isolated six alkylated …

Computational chemistry has always played a key role in anti-viral drug development. The
challenges and the quickly rising public interest when a virus is becoming a threat has …