Currently> 50 proteins have been reported to be associated with focal contacts and related
ECM adhesions. Most of these contain multiple domains through which they can interact …

Spermatogenesis is the process by which a single spermatogonium develops into 256
spermatozoa, one of which will fertilize the ovum. Since the 1950s when the stages of the …

Most strains of uropathogenic Escherichia coli (UPEC) encode filamentous adhesive
organelles called type 1 pili. We have determined that the type 1 pilus adhesin, FimH …

Cell adhesion is critical for the genesis and maintenance of both three-dimensional structure
and normal function in tissues. The biochemical entities mediating cell adhesion are …

Vinculin is a ubiquitously expressed actin-binding protein frequently used as a marker for
both cell–cell and cell–extracellular matrix (focal adhesion) adherens-type junctions, but its …

Cell to matrix adhesion regulates cellular homeostasis in multiple ways. Integrin attachment
to the extracellular matrix mediates this regulation through direct and indirect connections to …

Abstract α-catenin has often been considered to be a non-regulatory intercellular adhesion
protein, in contrast to β-catenin, which has well-documented dual roles in cell–cell adhesion …

Interactions of cells with the extracellular matrix are essential for the control of tissue
remodelling, cell migration, and embryogenesis. At the cell–extracellular matrix contact …

αE-catenin, a cadherin-associated protein, is required for tight junction (TJ) organization, but
its role is poorly understood. We transfected an αE-catenin–deficient colon carcinoma line …

La phospholipase D catalyse l'hydrolyse de la liaison phosphodiester des
glycérophospholipides, ce qui produit l'acide phosphatidique et un alcool polaire. Des …