Forced degradation studies have been used to simplify analytical methodology development
and achieve a deeper knowledge about the inherent stability of active pharmaceutical …

Background The importance of vitamin A to human health is neither a new nor emerging
topic; however, information regarding its primary food sources, chemical structure …

Retinoid-based drugs, while effective, are associated with systemic toxicity. Topical
alternatives offer a safer option, and tazarotene, a third-generation synthetic retinoid, holds …

Rationale Baricitinib (BARI), an inhibitor of Janus kinases 1 and 2 (JAK 1/2), is used for the
treatment of rheumatoid arthritis and COVID‐19. The present study focuses on establishing …

The drug substance, acalabrutinib was subjected to hydrolytic (acid, base and neutral) and
oxidative stress degradation as per ICH recommendations. Degradation products (DPs) …

The prime focus of the present study includes forced degradation studies on axitinib and the
characterization of novel degradation products formed. As per International Council for …

Mass balance in drug substances release testing is a critical quality attribute in
pharmaceutical manufacturing that continues to challenge modern analytical …

Exposure of a drug to UV irradiation could affect its physicochemical properties. Hence,
photostability testing is essential for topically administered drugs. Tazarotene, a receptor …

In the pharmaceutical industry, forced degradation tests are used to assess the stability of
drug samples. Examining degradation products under stress is beneficial for determining …