Mechanisms of organ fibrosis: Emerging concepts and implications for novel treatment strategies

I Lurje, NT Gaisa, R Weiskirchen, F Tacke - Molecular Aspects of Medicine, 2023 - Elsevier
Fibrosis, or tissue scarring, develops as a pathological deviation from the physiological
wound healing response and can occur in various organs such as the heart, lung, liver …

Identification, monitoring, and management of rheumatoid arthritis–associated interstitial lung disease

G Koduri, JJ Solomon - Arthritis & Rheumatology, 2023 - Wiley Online Library
Interstitial lung disease (ILD) is a frequent complication of rheumatoid arthritis (RA) that is
associated with a significant increase in mortality. Several risk factors for the development of …

Interstitial Lung Disease: A Review

TM Maher - JAMA, 2024 - jamanetwork.com
Importance Interstitial lung disease (ILD) consists of a group of pulmonary disorders
characterized by inflammation and/or fibrosis of the lung parenchyma associated with …

Efficacy of pirfenidone and nintedanib in interstitial lung diseases other than idiopathic pulmonary fibrosis: a systematic review

F Amati, A Stainer, V Polelli, M Mantero… - International Journal of …, 2023 - mdpi.com
Pirfenidone and nintedanib are antifibrotic medications approved for idiopathic pulmonary
fibrosis treatment by regulatory agencies and available for clinical use worldwide. These …

Survival of adults with rheumatoid arthritis associated interstitial lung disease-A systematic review and meta-analysis

HJ Farquhar, N Beckert, L Beckert, AL Edwards… - Seminars in Arthritis and …, 2023 - Elsevier
Background Rheumatoid arthritis associated interstitial lung disease (RA-ILD) is associated
with high levels of morbidity and mortality. The primary aim of this systematic review was to …

Effect of nintedanib in patients with progressive pulmonary fibrosis associated with rheumatoid arthritis: data from the INBUILD trial

EL Matteson, M Aringer, GR Burmester, H Mueller… - Clinical …, 2023 - Springer
Objectives Some patients with rheumatoid arthritis develop interstitial lung disease (RA-ILD)
that develops into progressive pulmonary fibrosis. We assessed the efficacy and safety of …

Treatable traits: a comprehensive precision medicine approach in interstitial lung disease

YH Khor, V Cottin, AE Holland, Y Inoue… - European …, 2023 - Eur Respiratory Soc
Interstitial lung disease (ILD) is a diverse group of inflammatory and fibrotic lung conditions
causing significant morbidity and mortality. A multitude of factors beyond the lungs influence …

Treatment outcomes for rheumatoid arthritis-associated interstitial lung disease: a real-world, multisite study of the impact of immunosuppression on pulmonary …

SM Matson, M Baqir, T Moua, M Marll, J Kent… - Chest, 2023 - Elsevier
Background Rheumatoid arthritis (RA)-associated interstitial lung disease (ILD) is common
in patients with RA and leads to significant morbidity and mortality. No randomized, placebo …

Interstitial lung disease in patients with anti-neutrophil cytoplasm antibody-associated vasculitis: an update on pathogenesis and treatment

D Turgeon, MS Balter, C Pagnoux - Current Opinion in Pulmonary …, 2023 - journals.lww.com
Interstitial lung disease in patients with anti-neutrophil c... : Current Opinion in Pulmonary
Medicine Interstitial lung disease in patients with anti-neutrophil cytoplasm antibody-associated …

Incidence, risk factors, and prognosis of acute exacerbation of rheumatoid arthritis-associated interstitial lung disease: a systematic review and meta-analysis

M Xie, C Zhu, Y Ye - BMC Pulmonary Medicine, 2023 - Springer
Introduction Acute exacerbation (AE) is a devastating complication of rheumatoid arthritis-
associated interstitial lung disease (RA-ILD) and leads to high mortality. This study aimed to …