Childhood stroke

PB Sporns, HJ Fullerton, S Lee, H Kim, WD Lo… - Nature Reviews …, 2022 - nature.com
Stroke is an important cause of neurological morbidity in children; most survivors have
permanent neurological deficits that affect the remainder of their life. Stroke in childhood, the …

Endovascular treatment in the multimodality management of brain arteriovenous malformations: report of the Society of NeuroInterventional Surgery Standards and …

R De Leacy, SA Ansari, CM Schirmer… - Journal of …, 2022 - jnis.bmj.com
Background The purpose of this review is to summarize the data available for the role of
angiography and embolization in the comprehensive multidisciplinary management of brain …

[HTML][HTML] Mutation of key signaling regulators of cerebrovascular development in vein of Galen malformations

S Zhao, KY Mekbib, MA van der Ent, G Allington… - Nature …, 2023 - nature.com
To elucidate the pathogenesis of vein of Galen malformations (VOGMs), the most common
and most severe of congenital brain arteriovenous malformations, we performed an …

Review of treatment and therapeutic targets in brain arteriovenous malformation

P Pan, S Weinsheimer, D Cooke… - Journal of Cerebral …, 2021 - journals.sagepub.com
Brain arteriovenous malformations (bAVM) are an important cause of intracranial
hemorrhage (ICH), especially in younger patients. The pathogenesis of bAVM are largely …

[HTML][HTML] An updated review on the genetics of arteriovenous malformations

K Maddy, A Chalamgari, O Ariwodo… - Gene & protein in …, 2023 - accscience.com
Arteriovenous malformations (AVM) are congenital malformations of the cerebral
vasculature resulting in pathological shunting of blood through dilated arteries and veins …

Emerging pathogenic mechanisms in human brain arteriovenous malformations: a contemporary review in the multiomics era

EA Winkler, MA Pacult, JS Catapano… - Neurosurgical …, 2022 - thejns.org
A variety of pathogenic mechanisms have been described in the formation, maturation, and
rupture of brain arteriovenous malformations (bAVMs). While the understanding of bAVMs …

Genetics of brain arteriovenous malformations and cerebral cavernous malformations

H Hongo, S Miyawaki, Y Teranishi, D Ishigami… - Journal of Human …, 2023 - nature.com
Cerebrovascular malformations comprise abnormal development of cerebral vasculature.
They can result in hemorrhagic stroke due to rupture of lesions as well as seizures and …

[HTML][HTML] 'De novo'brain AVMs—hypotheses for development and a systematic review of reported cases

IA Florian, L Beni, V Moisoiu, TL Timis, IS Florian… - Medicina, 2021 - mdpi.com
Background and Objectives: Brain arteriovenous malformations AVMs have been
consistently regarded as congenital malformations of the cerebral vasculature. However …

Somatic mutational landscape of extracranial arteriovenous malformations and phenotypic correlations

FN El Sissy, M Wassef, B Faucon… - Journal of the …, 2022 - Wiley Online Library
Background Somatic genetic variants may be the cause of extracranial arteriovenous
malformations, but few studies have explored these genetic anomalies, and no genotype …

[HTML][HTML] The Role and Therapeutic Implications of Inflammation in the Pathogenesis of Brain Arteriovenous Malformations

AR Ricciardelli, A Robledo, JE Fish, PT Kan, TH Harris… - Biomedicines, 2023 - mdpi.com
Brain arteriovenous malformations (bAVMs) are focal vascular lesions composed of
abnormal vascular channels without an intervening capillary network. As a result, high …