Molecular and metabolic orchestration of the lymphatic vasculature in physiology and pathology

N Montenegro-Navarro, C García-Báez… - Nature …, 2023 - nature.com
Lymphangiogenesis refers to the generation of new lymphatic vessels from pre-existing
ones. During development and particular adult states, lymphatic endothelial cells (LEC) …

FGFR families: biological functions and therapeutic interventions in tumors

Q Liu, J Huang, W Yan, Z Liu, S Liu, W Fang - MedComm, 2023 - Wiley Online Library
There are five fibroblast growth factor receptors (FGFRs), namely, FGFR1–FGFR5. When
FGFR binds to its ligand, namely, fibroblast growth factor (FGF), it dimerizes and …

Overexpression of carnitine palmitoyltransferase 1A promotes mitochondrial fusion and differentiation of glioblastoma stem cells

M Luo, YQ Liu, H Zhang, CH Luo, Q Liu… - Laboratory …, 2022 - nature.com
Glioma stem cells (GSCs) are self-renewing tumor cells with multi-lineage differentiation
potential and the capacity of construct glioblastoma (GBM) heterogenicity. Mitochondrial …

The role of lymphatic endothelial cell metabolism in lymphangiogenesis and disease

S Simeroth, P Yu - Frontiers in Cardiovascular Medicine, 2024 - frontiersin.org
Lymphatic endothelial cells (LECs) line lymphatic vessels, which play an important role in
the transport of lymph fluid throughout the human body. An organized lymphatic network …

Ectopic Fibroblast Growth Factor Signaling in Reprogramming Prostate Cancer Cell Metabolism and Immune Evasion

Y Ke - 2022 - oaktrust.library.tamu.edu
Prostate cancer (PCa) is the third leading cause of cancer death. The lack of an effective
cure for advanced stages and an overall low response to immunotherapy give prominence …