Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited
cause of kidney failure, accounting for 5%-10% of cases. Predicting which patients with …

Autosomal dominant polycystic kidney disease is a genetic disorder associated with
substantial variability in its natural course within and between affected families …

Renal biopsy is the gold-standard procedure to diagnose most of renal pathologies.
However, this invasive method is of limited repeatability and often describes an irreversible …

Capillary electrophoresis combined with mass spectrometry (CE‐MS) has been used for
several years for the investigation of proteins and peptides as biomarkers for diagnosis and …

The rate at which autosomal dominant polycystic kidney disease (ADPKD) progresses to
end-stage renal disease varies widely and is determined by genetic and non-genetic factors …

Autosomal dominant polycystic kidney disease (ADPKD) is a common cause of ESRD.
Affected individuals inherit a defective copy of either PKD1 or PKD2, which encode …

The natural history of autosomal dominant polycystic kidney disease (ADPKD) is
characterized by a variable rate of cyst development and increase in total kidney volume …

The biological functions of the Eph/ephrin system have been intensively investigated and
well documented so far since its discovery in 1987. Although the Eph/ephrin system has …

IgA nephropathy is the most common cause of primary glomerulonephritis. There are
different pathologic biopsy-based scoring systems in use, but there is no consensus among …

Urinary peptidomics focuses on endogenous urinary peptide content. Many studies now
show the usefulness of this approach for the discovery and validation of biomarkers in …