Personalized cancer vaccines (PCVs) are reinvigorating vaccine strategies in cancer
immunotherapy. In contrast to adoptive T-cell therapy and checkpoint blockade, the PCV …

Abstract Mucin 1 (MUC1) is a transmembrane mucin glycoprotein expressed on the surface
of almost all epithelial cells. Aberrantly glycosylated MUC1 is associated with cellular …

Wound management remains a major concern in clinical care. Conventional dressings and
hydrogels delivering drugs or cells can drive wound healing. However, these approaches …

O-glycosylation is a highly frequent post-translation modification of proteins, with important
functional implications in both physiological and disease contexts. The biosynthesis of O …

The transformation from normal to malignant phenotype in human cancers is associated with
aberrant cell-surface glycosylation. It has frequently been reported that MUC1, the heavily …

Conspectus Cancer vaccines provide an efficient strategy to enhance tumor-specific
immune responses by redeploying immune systems. Despite the approval of the first cancer …

Glycans are key players in many biological processes. They are essential for protein folding
and stability and act as recognition elements in cell–cell and cell–matrix interactions. Thus …

Currently, there is renewed interest in attempting to recruit the host immune system to
eliminate cancers, and within this renewed activity, MUC1 continues to arouse interest …

Vaccination is one of the greatest achievements in biomedical research preventing death
and morbidity in many infectious diseases through the induction of pathogen‐specific …

Mucin1 is a highly glycosylated type 1 transmembrane mucin that ranks second among 75
tumor-related antigens published by the National Cancer Institute, and has been identified …