The origin and diversity of the HIV-1 pandemic

J Hemelaar - Trends in molecular medicine, 2012 - cell.com
This review examines the enormous progress that has been made in the past decade in
understanding the origin of HIV, HIV genetic variability, and the impact of global HIV diversity …

Acute HIV-1 infection

MS Cohen, GM Shaw, AJ McMichael… - New England Journal …, 2011 - Mass Medical Soc
Acute HIV-1 Infection | New England Journal of Medicine Skip to main content Access provided
byTE WHATU ORA HEALTH NEW ZEALAND COUNTIES MANUKAU The New England …

HIV transmission

GM Shaw, E Hunter - Cold Spring Harbor …, 2012 - perspectivesinmedicine.cshlp.org
HIV-1 is transmitted by sexual contact across mucosal surfaces, by maternal-infant
exposure, and by percutaneous inoculation. For reasons that are still incompletely …

Generation of transmitted/founder HIV-1 infectious molecular clones and characterization of their replication capacity in CD4 T lymphocytes and monocyte-derived …

C Ochsenbauer, TG Edmonds, H Ding… - Journal of …, 2012 - Am Soc Microbiol
Genome sequences of transmitted/founder (T/F) HIV-1 have been inferred by analyzing
single genome amplicons of acute infection plasma viral RNA in the context of a …

Low-frequency HIV-1 drug resistance mutations and risk of NNRTI-based antiretroviral treatment failure: a systematic review and pooled analysis

JZ Li, R Paredes, HJ Ribaudo, ES Svarovskaia… - Jama, 2011 - jamanetwork.com
Context Presence of low-frequency, or minority, human immunodeficiency virus type 1 (HIV-
1) drug resistance mutations may adversely affect response to antiretroviral treatment (ART) …

[HTML][HTML] Vaccine-induced protection from homologous tier 2 SHIV challenge in nonhuman primates depends on serum-neutralizing antibody titers

MG Pauthner, JP Nkolola, C Havenar-Daughton… - Immunity, 2019 - cell.com
Passive administration of HIV neutralizing antibodies (nAbs) can protect macaques from
hard-to-neutralize (tier 2) chimeric simian-human immunodeficiency virus (SHIV) challenge …

Sequential bottlenecks drive viral evolution in early acute hepatitis C virus infection

RA Bull, F Luciani, K McElroy, S Gaudieri… - PLoS …, 2011 - journals.plos.org
Hepatitis C is a pandemic human RNA virus, which commonly causes chronic infection and
liver disease. The characterization of viral populations that successfully initiate infection, and …

Transmission of single HIV-1 genomes and dynamics of early immune escape revealed by ultra-deep sequencing

W Fischer, VV Ganusov, EE Giorgi, PT Hraber… - PloS one, 2010 - journals.plos.org
We used ultra-deep sequencing to obtain tens of thousands of HIV-1 sequences from
regions targeted by CD8+ T lymphocytes from longitudinal samples from three acutely …

High multiplicity infection by HIV-1 in men who have sex with men

H Li, KJ Bar, S Wang, JM Decker, Y Chen, C Sun… - PLoS …, 2010 - journals.plos.org
Elucidating virus-host interactions responsible for HIV-1 transmission is important for
advancing HIV-1 prevention strategies. To this end, single genome amplification (SGA) and …

Resistance to type 1 interferons is a major determinant of HIV-1 transmission fitness

SS Iyer, F Bibollet-Ruche… - Proceedings of the …, 2017 - National Acad Sciences
Sexual transmission of HIV-1 is an inefficient process, with only one or few variants of the
donor quasispecies establishing the new infection. A critical, and as yet unresolved …