Intrinsic and extrinsic pathways of apoptosis: Role in cancer development and prognosis

D Kashyap, VK Garg, N Goel - Advances in protein chemistry and structural …, 2021 - Elsevier
Apoptosis, also named programmed cell death, is a fundament process required for
morphogenetic homeostasis during early development and in pathophysiological …

Overview of artificial intelligence in breast cancer medical imaging

D Zheng, X He, J Jing - Journal of Clinical Medicine, 2023 - mdpi.com
The heavy global burden and mortality of breast cancer emphasize the importance of early
diagnosis and treatment. Imaging detection is one of the main tools used in clinical practice …

Update on gastric cancer treatments and gene therapies

A Biagioni, I Skalamera, S Peri, N Schiavone… - Cancer and Metastasis …, 2019 - Springer
Gastric cancer is an active topic of clinical and basic research due to high morbidity and
mortality. To date, gastrectomy and chemotherapy are the only therapeutic options for gastric …

Unravelling tumour heterogeneity using next-generation imaging: radiomics, radiogenomics, and habitat imaging

E Sala, E Mema, Y Himoto, H Veeraraghavan… - Clinical radiology, 2017 - Elsevier
Tumour heterogeneity in cancers has been observed at the histological and genetic levels,
and increased levels of intra-tumour genetic heterogeneity have been reported to be …

Prediction models applying machine learning to oral cavity cancer outcomes: a systematic review

J Adeoye, JY Tan, SW Choi, P Thomson - International journal of medical …, 2021 - Elsevier
Objectives Machine learning platforms are now being introduced into modern oncological
practice for classification and prediction of patient outcomes. To determine the current status …

[HTML][HTML] Current advances in prognostic and diagnostic biomarkers for solid cancers: Detection techniques and future challenges

M Pal, T Muinao, HPD Boruah, N Mahindroo - Biomedicine & …, 2022 - Elsevier
Solid cancers are one of the leading causes of cancer related deaths, characterized by rapid
growth of tumour, and local and distant metastases. Current advances on multimodality care …

Combining molecular and imaging metrics in cancer: radiogenomics

R Lo Gullo, I Daimiel, EA Morris, K Pinker - Insights into imaging, 2020 - Springer
Background Radiogenomics is the extension of radiomics through the combination of
genetic and radiomic data. Because genetic testing remains expensive, invasive, and time …

PTEN as a prognostic/predictive biomarker in cancer: an unfulfilled promise?

C Bazzichetto, F Conciatori, M Pallocca, I Falcone… - Cancers, 2019 - mdpi.com
Identifying putative biomarkers of clinical outcomes in cancer is crucial for successful
enrichment, and for the selection of patients who are the most likely to benefit from a specific …

A regression tree approach to identifying subgroups with differential treatment effects

WY Loh, X He, M Man - Statistics in medicine, 2015 - Wiley Online Library
In the fight against hard‐to‐treat diseases such as cancer, it is often difficult to discover new
treatments that benefit all subjects. For regulatory agency approval, it is more practical to …

Current molecular-targeted therapies in NSCLC and their mechanism of resistance

Z Schrank, G Chhabra, L Lin, T Iderzorig, C Osude… - Cancers, 2018 - mdpi.com
Lung cancer is treated with many conventional therapies, such as surgery, radiation, and
chemotherapy. However, these therapies have multiple undesirable side effects. To bypass …