The identification of promoters and their regulatory elements is one of the major challenges
in bioinformatics and integrates comparative, structural, and functional genomics. Many …

Cytokinins are classic plant hormones that orchestrate plant growth, development, and
physiology. They affect gene expression in target cells by activating a multistep …

Genomics is a highly cross-disciplinary field that creates paradigm shifts in such diverse
areas as medicine and agriculture. It is believed that many significant scientific and …

Here we propose a new determinant for localization of nucleosomes along genomic DNA, in
addition to sequence-dependent features. The new specific class of chromatin scaling …

DNA sequence has long been recognized as an important contributor to nucleosome
positioning, which has the potential to regulate access to genes. The extent to which the …

Motivation: Frequency-domain analysis of biomolecular sequences is hindered by their
representation as strings of characters. If numerical values are assigned to each of these …

Computational prediction of eukaryotic polII promoters has been one of the most elusive
problems despite considerable effort devoted to the study. Researchers have looked for …

Human genome sequencing has resulted in a great body of data, including a stunningly
large number of single nucleotide polymorphisms (SNPs) with unknown phenotypic …

Motivation: Genomic sequences are highly redundant and contain many types of repetitive
DNA. Fuzzy tandem repeats (FTRs) are of particular interest. They are found in regulatory …

Motivation: Although a great deal of research has been undertaken in the area of promoter
prediction, prediction techniques are still not fully developed. Many algorithms tend to exhibit …