Neuroimaging of pain in animals allows us to better understand mechanisms of pain
processing and modulation. In this review, we discuss recently published brain imaging …

All experimental models of osteoarthritis (OA)-like joint damage are accompanied by
behaviors indicative of pain. In experimental knee OA, evoked pain responses to …

Chronic pain often predicts the onset of psychological distress. Symptoms including anxiety
and depression after pain chronification reportedly are caused by brain remodeling …

Huoxuezhitong capsule (HXZT, activating blood circulation and relieving pain capsule), has
been applied for osteoarthritis since 1974. It consists of Angelica sinensis (Oliv.) Diels …

Manganese-enhanced magnetic resonance imaging (MEMRI) rose to prominence in the
1990s as a sensitive approach to high contrast imaging. Following the discovery of …

Chronic pain is a major health problem, affecting 10–30% of the population in developed
countries. While chronic pain is defined as “a persistent complaint of pain lasting for more …

Patients with severe traumatic peripheral nerve injury (PNI) always suffer from incomplete
recovery and poor functional outcome. Physical exercise-based rehabilitation, as a non …

Chemotherapy-induced neuropathy (CIN) is one of the most common complications of
cancer treatment with sensory dysfunctions which frequently include pain. The mechanisms …

Although chronic pain states have been associated with impaired cognitive functions,
including memory and cognitive flexibility, the cognitive effects of osteoarthritis (OA) pain …

Neuropathic pain induced by a nerve injury can lead to chronic pain. Recent studies have
reported hyperactive neural activities in the nociceptive-related area of the brain as a result …