Within patients with sepsis, there exists significant heterogeneity, and while all patients
should receive conventional therapy, there are subgroups of patients who may benefit from …

Inflammation drives pathology in many human diseases for which there are no disease-
modifying drugs. Inflammasomes are signalling platforms that can induce pathological …

Human interleukin-1β (IL-1β) is a pro-inflammatory cytokine that plays a critical role in the
regulation of the immune response and the development of various inflammatory diseases …

Protein–protein interactions mediate most molecular processes in the cell, offering a
significant opportunity to expand the set of known druggable targets. Unfortunately, targeting …

The human interleukin-1 receptor I (IL-1R1) is a cytokine receptor recognized by interleukin
1β (IL-1β), among other cytokines. Over activation of IL-1R1 has been implicated in various …

The interleukin (IL)-1 family is a major proinflammatory cytokine family, ranging from the well-
studied IL-1s to the most recently discovered IL-33. As a new focus, IL-33 has attracted …

Background Acne vulgaris is a skin infection widely seen in adolescents between 10–19
years with males affected more than females. It mainly affects the face but may also affect the …

Cuscuta chinensis (C. chinensis) presents many pharmacological activities, including
antidiabetic effects, and antioxidant, anti-inflammatory, and antitumor properties. However …

High‐resolution nuclear magnetic resonance (NMR) spectroscopy represents a key
methodology for studying biomolecules and their interplay with other molecules. Recent …

Abstract Inflammatory Bowel Disease (IBD) are chronic and recurrent inflammatory disorders
affecting the gastrointestinal tract, characterized by the involvement of numerous pro …