Rapid and timely diagnosis of infectious diseases is a critical determinant of clinical
outcomes and general public health. For the detection of various pathogens, microfluidics …

Cancer-derived small extracellular vesicles (sEVs) are specific subgroups of lipid bilayer
vesicles secreted from cancer cells to the extracellular environment. They carry distinct …

The rapid spread of COVID-19 across the world has revealed major gaps in our ability to
respond to new virulent pathogens. Rapid, accurate, and easily configurable molecular …

Isotachophoresis (ITP) is a versatile electrophoretic technique that can be used for sample
preconcentration, separation, purification, and mixing, and to control and accelerate …

Fast and reliable diagnoses are invaluable in clinical care. Samples (eg, blood, urine, and
saliva) are collected and analyzed for various biomarkers to quickly and sensitively assess …

One of the important pursuits in science and engineering research today is to develop low-
cost and user-friendly technologies to improve the health of people. Over the past decade …

Nucleic acid amplification tests (NAATs) are a crucial diagnostic and monitoring tool for
infectious diseases. A key procedural step for NAATs is sample preparation: separating and …

The simultaneous analysis of RNA and DNA of single cells remains a challenge as these
species have very similar physical and biochemical properties and can cross-contaminate …

Reviewed are methods of nucleic acid (NA) extraction and sample preparation using an
electrophoretic purification and focusing method called isotachophoresis (ITP). ITP requires …

Ebola virus disease (EVD) is a devastating, highly infectious illness with a high mortality
rate. The disease is endemic to regions of Central and West Africa, where there is limited …