[HTML][HTML] Biomedical importance of indoles

NK Kaushik, N Kaushik, P Attri, N Kumar, CH Kim… - Molecules, 2013 - mdpi.com
The indole nucleus is an important element of many natural and synthetic molecules with
significant biological activity. This review covers some of the relevant and recent …

Marine natural products

JW Blunt, BR Copp, MHG Munro, PT Northcote… - Natural product …, 2011 - pubs.rsc.org
Covering: 2009. Previous review: Nat. Prod. Rep., 2010, 27, 165 This review covers the
literature published in 2009 for marine natural products, with 857 citations (588 for the …

Muscarine, imidazole, oxazole, and thiazole alkaloids

Z Jin - Natural product reports, 2011 - pubs.rsc.org
Covering: July 2007 to June 2010. Previous review: Nat. Prod. Rep., 2009, 26, 382–445 A
great number of structurally diverse natural products containing five-membered heterocyclic …

Anti-cancer nitrogen-containing heterocyclic compounds

Z Hosseinzadeh, A Ramazani… - Current Organic …, 2018 - ingentaconnect.com
Cancer is one of the leading causes of death worldwide. Mutation of the cell regulates genes
and protein causing cancer. Surgery, radiotherapy, and the use of anticancer agents are the …

Tryptophan derived natural marine alkaloids and synthetic derivatives as promising antimicrobial agents

MC Almeida, DISP Resende, PM da Costa… - European journal of …, 2021 - Elsevier
Antimicrobial resistance has become a major threat to public health worldwide, as
pathogenic microorganisms are finding ways to evade all known antimicrobials. Therefore …

[HTML][HTML] Cascade reaction based synthetic strategies targeting biologically intriguing indole polycycles

MG Ciulla, S Zimmermann, K Kumar - Organic & Biomolecular …, 2019 - pubs.rsc.org
Indole polycycles are common structural frameworks of biologically intriguing small
molecules of natural and synthetic origin and therefore remain interesting and challenging …

β-Carboline-based molecular hybrids as anticancer agents: A brief sketch

JP Soni, Y Yeole, N Shankaraiah - RSC Medicinal Chemistry, 2021 - pubs.rsc.org
Cancer is a huge burden on the healthcare system and is foremost cause of mortality across
the globe. Among various therapeutic strategies, chemotherapy plays an enormous role in …

Synthesis of extended conjugated indolyl chalcones as potent anti-breast cancer, anti-inflammatory and antioxidant agents

PS Bhale, HV Chavan, SB Dongare… - Bioorganic & medicinal …, 2017 - Elsevier
In the present investigation, synthesis of a series of extended conjugated δ-chloro-α-cyano
substituted indolyl chalcones (5a–p) was accomplished by reacting 3-cyanoacetylindole 2 …

[HTML][HTML] Halogenated indole alkaloids from marine invertebrates

PM Pauletti, LS Cintra, CG Braguine, AAS Filho… - Marine drugs, 2010 - mdpi.com
This review discusses the isolation, structural elucidation, and biological activities of
halogenated indole alkaloids obtained from marine invertebrates. Meridianins and related …

Emergence of diversity and stereochemical outcomes in the biosynthetic pathways of cyclobutane-centered marine alkaloid dimers

MA Beniddir, L Evanno, D Joseph, A Skiredj… - Natural product …, 2016 - pubs.rsc.org
Covering: up to 2016 Dictazoles and sceptrins are singular metabolites of marine origin. The
present dichotomic case study provides a comprehensive perspective on these cyclobutane …