Treatment optimization in MS: Canadian MS Working Group updated recommendations

MS Freedman, D Selchen, DL Arnold, A Prat… - Canadian Journal of …, 2013 - cambridge.org
The Canadian Multiple Sclerosis Working Group (CMSWG) developed practical
recommendations in 2004 to assist clinicians in optimizing the use of disease-modifying …

Multiple sclerosis in children: an update on clinical diagnosis, therapeutic strategies, and research

A Waldman, A Ghezzi, A Bar-Or, Y Mikaeloff… - The Lancet …, 2014 - thelancet.com
The clinical features, diagnostic challenges, neuroimaging appearance, therapeutic options,
and pathobiological research progress in childhood—and adolescent—onset multiple …

How patients with multiple sclerosis acquire disability

FD Lublin, DA Häring, H Ganjgahi, A Ocampo… - Brain, 2022 - academic.oup.com
Patients with multiple sclerosis acquire disability either through relapse-associated
worsening (RAW) or progression independent of relapse activity (PIRA). This study …

Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria

CH Polman, SC Reingold, B Banwell… - Annals of …, 2011 - Wiley Online Library
New evidence and consensus has led to further revision of the McDonald Criteria for
diagnosis of multiple sclerosis. The use of imaging for demonstration of dissemination of …

Clinical, environmental, and genetic determinants of multiple sclerosis in children with acute demyelination: a prospective national cohort study

B Banwell, A Bar-Or, DL Arnold, D Sadovnick… - The Lancet …, 2011 - thelancet.com
Summary Background HLA-DRB1* 15 genotype, previous infection with Epstein-Barr virus,
and vitamin D insufficiency are susceptibility factors for multiple sclerosis, but whether they …

Diagnostic algorithm for relapsing acquired demyelinating syndromes in children

Y Hacohen, K Mankad, WK Chong, F Barkhof… - Neurology, 2017 - AAN Enterprises
Objective: To establish whether children with relapsing acquired demyelinating syndromes
(RDS) and myelin oligodendrocyte glycoprotein antibodies (MOG-Ab) show distinctive …

Antibodies to MOG are transient in childhood acute disseminated encephalomyelitis

AK Pröbstel, K Dornmair, R Bittner, P Sperl, D Jenne… - Neurology, 2011 - AAN Enterprises
Objective: To study the longitudinal dynamics of anti–myelin oligodendrocyte glycoprotein
(MOG) autoantibodies in childhood demyelinating diseases. Methods: We addressed the …

Incidence of acquired demyelination of the CNS in Canadian children

B Banwell, J Kennedy, D Sadovnick, DL Arnold… - Neurology, 2009 - AAN Enterprises
Background: The incidence of acquired demyelination of the CNS (acquired demyelinating
syndromes [ADS]) in children is unknown. It is important that physicians recognize the …

Cognitive and psychosocial features in childhood and juvenile MS: two-year follow-up

MP Amato, B Goretti, A Ghezzi, S Lori, V Zipoli… - Neurology, 2010 - AAN Enterprises
Objective: To assess the evolution of cognitive and psychosocial functioning in a cohort of
childhood and juvenile multiple sclerosis (MS) cases after a mean period of 2 years had …

Clinical characteristics and disability progression of early-and late-onset multiple sclerosis compared to adult-onset multiple sclerosis

O Mirmosayyeb, S Brand, M Barzegar… - Journal of clinical …, 2020 - mdpi.com
Background: Compared to the adult onset of multiple sclerosis (AOMS), both early-onset
(EOMS) and late-onset (LOMS) are much less frequent, but are often under-or …