Solid self emulsifying drug delivery system: Superior mode for oral delivery of hydrophobic cargos

I Maji, S Mahajan, A Sriram, P Medtiya… - Journal of Controlled …, 2021 - Elsevier
A significant proportion of recently approved drug molecules possess poor aqueous
solubility which further restrains their desired bioavailability. Poor aqueous solubility of these …

[PDF][PDF] An overview of therapeutic effects of vanillic acid

N Sharma, N Tiwari, M Vyas, N Khurana… - Plant Arch, 2020 - academia.edu
Vanillic acid (VA) is a derivative of benzoic acid which is used as a flavouring agent,
preservative, and food additive in the food industry. VA is phenolic molecule that is oxidized …

Curcumin nanoformulations to combat aging-related diseases

M Mahjoob, U Stochaj - Ageing Research Reviews, 2021 - Elsevier
Aging increases the susceptibility to a diverse set of diseases and disorders, including
neurodegeneration, cancer, diabetes, and arthritis. Natural compounds are currently being …

Oral nano drug delivery systems for the treatment of type 2 diabetes mellitus: an available administration strategy for antidiabetic phytocompounds

X Nie, Z Chen, L Pang, L Wang, H Jiang… - International journal …, 2020 - Taylor & Francis
In view of the worldwide serious health threat of type 2 diabetes mellitus (T2DM), natural
sources of chemotherapies have been corroborated as the promising alternatives, with the …

Curcumin-based nanotechnology approaches and therapeutics in restoration of autoimmune diseases

N Rahiman, YV Markina, P Kesharwani… - Journal of Controlled …, 2022 - Elsevier
Autoimmune diseases usually arise as a result of an aberrant immune system attack on
normal tissues of the body, which leads to a cascade of inflammatory reactions. The immune …

Enhanced oral bioavailability and neuroprotective effect of fisetin through its SNEDDS against rotenone-induced Parkinson's disease rat model

R Kumar, R Kumar, N Khurana, SK Singh… - Food and Chemical …, 2020 - Elsevier
Fisetin (FS) was reported to have various pharmacological activities. But due to its lower
aqueous solubility and oral bioavailability, it is not in much use. As solubility and …

The trend of organic based nanoparticles in the treatment of diabetes and its perspectives

V Natesan, SJ Kim - Biomolecules & therapeutics, 2022 - pmc.ncbi.nlm.nih.gov
Diabetes is an untreatable metabolic disorder characterized by alteration in blood sugar
homeostasis, with submucosal insulin therapy being the primary treatment option. This route …

Exploring role of probiotics and Ganoderma lucidum extract powder as solid carriers to solidify liquid self-nanoemulsifying delivery systems loaded with curcumin

R Khursheed, SK Singh, S Wadhwa, M Gulati… - Carbohydrate …, 2020 - Elsevier
Solid self-nanoemulsifying drug delivery system (S-SENDDS) containing Curcumin (CRM)
were prepared using combination of Ganoderma lucidum extract powder (GLEP) and …

Solid self-nano emulsifying nanoplatform loaded with tamoxifen and resveratrol for treatment of breast cancer

N Shrivastava, A Parikh, RP Dewangan, L Biswas… - Pharmaceutics, 2022 - mdpi.com
The solid self-nanoemulsifying drug delivery system (s-SNEDDS) is a growing platform for
the delivery of drugs via oral route. In the present work, tamoxifen (TAM) was loaded in …

Self-nanoemulsifying composition containing curcumin, quercetin, Ganoderma lucidum extract powder and probiotics for effective treatment of type 2 diabetes mellitus …

R Khursheed, SK Singh, B Kumar, S Wadhwa… - International Journal of …, 2022 - Elsevier
Liquid self-nanoemulsifying drug delivery system (L-SNEDDS) of curcumin and quercetin
were prepared by dissolving them in isotropic mixture of Labrafil M1944CS®, Capmul …