[HTML][HTML] Gene environment interactions in the etiology of neural tube defects

RH Finnell, CD Caiaffa, SE Kim, Y Lei, J Steele… - Frontiers in …, 2021 - frontiersin.org
Human structural congenital malformations are the leading cause of infant mortality in the
United States. Estimates from the United States Center for Disease Control and Prevention …

Review about gabapentin misuse, interactions, contraindications and side effects

GC Quintero - Journal of experimental pharmacology, 2017 - Taylor & Francis
The current work is targeted to review the risks of gabapentin misuse, its potential
interactions with other drugs, side effects and use contraindications. This review consists of …

Risks of 23 specific malformations associated with prenatal exposure to 10 antiepileptic drugs

PO Blotière, F Raguideau, A Weill, E Elefant, I Perthus… - Neurology, 2019 - AAN Enterprises
Objective To assess the association between exposure to monotherapy with 10 different
antiepileptic drugs (AEDs) during the first 2 months of pregnancy and the risk of 23 major …

Neurodevelopmental outcomes in children exposed to newer antiseizure medications: A systematic review

R Knight, A Wittkowski, RL Bromley - Epilepsia, 2021 - Wiley Online Library
As prenatal exposure to certain older antiseizure medications (ASMs) has been linked with
poorer neurodevelopmental outcomes in children, the use of newer ASMs throughout …

[HTML][HTML] Italian guidelines for primary headaches: 2012 revised version

P Sarchielli, F Granella, MP Prudenzano… - The Journal of …, 2012 - Springer
The first edition of the Italian diagnostic and therapeutic guidelines for primary headaches in
adults was published in J Headache Pain 2 (Suppl. 1): 105–190 (2001). Ten years later, the …

Antiepileptic drugs and pregnancy outcomes

BJ Wlodarczyk, AM Palacios… - American journal of …, 2012 - Wiley Online Library
The treatment of epilepsy in women of reproductive age remains a clinical challenge. While
most women with epilepsy (WWE) require anticonvulsant drugs for adequate control of their …

Developmental effects of antiepileptic drugs and the need for improved regulations

KJ Meador, DW Loring - Neurology, 2016 - AAN Enterprises
Antiepileptic drugs (AEDs) are among the most common teratogenic drugs prescribed to
women of childbearing age. AEDs can induce both anatomical (malformations) and …

Risk of early neurodevelopmental outcomes associated with prenatal exposure to the antiepileptic drugs most commonly used during pregnancy: a French nationwide …

PO Blotière, S Miranda, A Weill, Y Mikaeloff, H Peyre… - BMJ open, 2020 - bmjopen.bmj.com
Objectives To assess the association between prenatal exposure to monotherapy with the
antiepileptic drugs (AEDs) most commonly used during pregnancy and the risk of various …

Carbamazepine adverse drug reactions

I Fricke-Galindo, A LLerena, H Jung-Cook… - Expert review of …, 2018 - Taylor & Francis
Introduction: Carbamazepine (CBZ) is used for the treatment of epilepsy and other
neurological and psychiatric disorders. The occurrence of adverse reactions (ADRs) to CBZ …

[HTML][HTML] Cytochrome P450-dependent biotransformation capacities in embryonic, juvenile and adult stages of zebrafish (Danio rerio)—a state-of-the-art review

AK Loerracher, T Braunbeck - Archives of Toxicology, 2021 - Springer
Given the strong trend to implement zebrafish (Danio rerio) embryos as translational model
not only in ecotoxicological, but also toxicological testing strategies, there is an increasing …