New insights into atopic dermatitis: role of skin barrier and immune dysregulation

DYM Leung - Allergology international, 2013 - jstage.jst.go.jp
Atopic dermatitis (AD) is a chronic inflammatory skin disease that is often associated with the
development of food allergy and asthma. New insights into AD reveals an important role for …

The genetics and epigenetics of atopic dermatitis—filaggrin and other polymorphisms

Y Liang, C Chang, Q Lu - Clinical reviews in allergy & immunology, 2016 - Springer
Atopic dermatitis (AD) is a chronic inflammatory skin disease caused by a combination of
genetic and environmental factors. Genetic evidences depict a complex network comprising …

Basophils promote innate lymphoid cell responses in inflamed skin

BS Kim, K Wang, MC Siracusa, SA Saenz… - The Journal of …, 2014 - journals.aai.org
Type 2 inflammation underlies allergic diseases such as atopic dermatitis, which is
characterized by the accumulation of basophils and group 2 innate lymphoid cells (ILC2s) in …

Atopic dermatitis 2.0: from the clinical phenotype to the molecular taxonomy and stratified medicine

TH Bieber - Allergy, 2012 - Wiley Online Library
Atopic dermatitis (AD) is a paradigmatic inflammatory chronic skin disease. As for other
chronic skin diseases,(i) the spectrum of the clinical phenotype and severity as well as (ii) …

Biomarkers associated with the development of comorbidities in patients with atopic dermatitis: a systematic review

C Broderick, S Ziehfreund, K van Bart, B Arents… - Allergy, 2023 - Wiley Online Library
Biomarkers associated with the development of comorbidities in atopic dermatitis (AD)
patients have been reported, but have not yet been systematically reviewed. Seven …

[HTML][HTML] Molecular genetic of atopic dermatitis: an update

HA Al-Shobaili, AA Ahmed, N Alnomair… - … journal of health …, 2016 - ncbi.nlm.nih.gov
Atopic dermatitis (AD) is a chronic multifactorial inflammatory skin disease. The
pathogenesis of AD remains unclear, but the disease results from dysfunctions of skin …

Past, present, and future for biologic intervention in atopic dermatitis

MD Howell, ML Parker, T Mustelin, K Ranade - Allergy, 2015 - Wiley Online Library
Atopic dermatitis (AD) is a debilitating disease that significantly alters the quality of life for
one in four children and one in 10 adults. Current management of AD utilizes combinations …

Peanut-specific type 1 regulatory T cells induced in vitro from allergic subjects are functionally impaired

L Pellerin, JA Jenks, S Chinthrajah… - Journal of Allergy and …, 2018 - Elsevier
Background Peanut allergy (PA) is a life-threatening condition that lacks regulator-approved
treatment. Regulatory T type 1 (TR 1) cells are potent suppressors of immune responses and …

Childhood atopic dermatitis: current developments, treatment approaches, and future expectations

PG Çetinkaya, ÜM Şahiner - Turkish journal of medical …, 2019 - journals.tubitak.gov.tr
Atopic dermatitis (AD) is the most common chronic inflammatory skin disorder of childhood.
Underlying factors that contribute to AD are impaired epithelial barrier, alterations in the lipid …

Association between IL-6 polymorphisms and Atopic Dermatitis in Chinese Han children

S Huang, H Wang, H Zheng, W Li, J Shi, C Shen… - Frontiers in …, 2023 - frontiersin.org
Introduction Atopic Dermatitis (AD) is a chronic inflammatory skin disease that affects almost
20% of children and 2-10% of adults worldwide. Previous studies revealed that Interleukin-6 …