Flavonoids are interesting molecules synthetized by plants. They can be found abundantly
in seeds and fruits, determining the color, flavor, and other organoleptic characteristics, as …

Various signaling mechanisms contribute significantly to the development of multiple
cancers. Small molecules with the potential of influencing a wide variety of molecular targets …

Cancer is a heterogeneous disease and one of the major issues of health concern,
especially for the public health system globally. Nature is a source of anticancer drugs with …

Multidrug resistance (MDR) resulting from different defensive mechanisms in cancer is one
of the major obstacles of clinical treatment. To circumvent MDR many reversal agents have …

Simple Summary Common flavonoid luteolin 3′, 4′, 5, 7-tetrahydroxyflavone has
immense potential to be utilized as a chemopreventive dietary molecule. According to …

Flavonoids have been shown to have anti-oxidative effects, as well as other health benefits
(eg, anti-inflammatory and anti-tumor functions). Luteolin (3′, 4′, 5, 7-tetrahydroxyflavone) …

Background Monitoring target engagement at various stages of drug development is
essential for natural product (NP)-based drug discovery and development. The cellular …

Pancreatic adenocarcinoma is a disease with no effective treatment. Chemo-resistance
contributes to the dismal prognosis for patients diagnosed with the disease. This study aims …

Regulated cell death (RCD) refers to programmed cell death regulated by various protein
molecules, such as apoptosis, autophagy‐dependent cell death, and necroptosis …

There are abundant sources of anticancer drugs in nature that have a broad prospect in
anticancer drug discovery. Natural compounds, with biological activities extracted from …