Since an immunoreceptor tyrosine‐based inhibition motif (ITIM) was first identified in the
intracytoplasmic domain of FcγRIIB, ITIMs have been found in a large number of inhibitory …

▪ Abstract This review addresses issues related to the evolution of the complex multigene
families of antigen binding receptors that function in adaptive immunity. Advances in …

The coxsackievirus and adenovirus receptor (CAR) mediates cell attachment and infection
by coxsackie B viruses and by a number of adenoviruses. CAR also mediates homotypic …

Vertebrate organisms have evolved sophisticated immunological mechanisms for the
recognition of self versus nonself. The immune system is functionally characterized by …

In an attempt to elucidate the molecular mechanisms underlying neuro-network formation in
the developing brain, we analyzed 130 proteolytic cleavage peptides of membrane proteins …

To gain fundamental information regarding the molecular basis of endothelial cell adhesive
interactions during vascular formation, we have cloned and characterized a unique cell …

Mouse monoclonal antibody A33 (mAb A33) recognizes a M r 43,000 cell surface
glycoprotein (designated A33) expressed in human colonic epithelium and colon cancer but …

The coxsackie-and adenovirus receptor (CAR) is a transmembrane protein belonging to the
immunoglobulin superfamily. The function of CAR as a virus receptor has been extensively …

We used mRNA differential display methodology to analyze the shift of transcription profile
induced by the fish rhabdovirus, viral hemorrhagic septicemia virus (VHSV), in rainbow trout …

The development of immune checkpoint inhibitors is becoming a promising approach to fight
cancers. Antibodies targeting immune checkpoint proteins such as CTLA-4 and PD-1 can …