Advances in point-of-care optical biosensing for underserved populations

N Chaturvedi, A Goncharov, S Tripathy… - TrAC Trends in …, 2024 - Elsevier
Portable optical biosensors have been created over the last 30 years for detecting molecular
and cellular targets. More recently, advances in algorithms, readers, and materials have …

Point-of-care isothermal nucleic acid amplification tests: progress and bottlenecks for extraction-free sample collection and preparation

AF Wilkinson, MJ Barra, EN Novak… - Expert Review of …, 2024 - Taylor & Francis
Introduction Suitable sample collection and preparation methods are essential to enable
nucleic acid amplification testing at the point of care (POC). Strategies that allow direct …

A portable, integrated microfluidics for rapid and sensitive diagnosis of Streptococcus agalactiae in resource-limited environments

Z Wang, B Yan, Y Ni, Y Cao, J Qiu, R He… - Biosensors and …, 2024 - Elsevier
Abstract Streptococcus agalactiae (Group B Streptococcus, GBS) has been the leading
cause of infections in newborns. Rapid and accurate diagnosis of GBS in pregnant women …

Detection of high-risk HPV 16 genotypes in cervical cancers using isothermal DNA amplification with electrochemical genosensor

P Nakowong, P Chatchawal, T Chaibun… - Talanta, 2024 - Elsevier
Cervical cancer emerges as the third most prevalent types of malignancy among women on
a global scale. Cervical cancer is significantly associated with the persistent infection of …

A portable all-in-one microfluidic device with real-time colorimetric LAMP for HPV16 and HPV18 DNA point-of-care testing

H Bai, Y Liu, L Gao, T Wang, X Zhang, J Hu… - Biosensors and …, 2024 - Elsevier
Screening for high-risk human papillomavirus (HPV) infection is one of the most important
preventative measures for cervical cancer. However, fast, convenient, and low-cost HPV …

A novel tailed primer nucleic acid test for detection of HPV 16, 18 and 45 DNA at the point of care

MM Chang, A Ma, EN Novak, M Barra, KA Kundrod… - Scientific reports, 2023 - nature.com
Cervical cancer is a leading cause of death for women in low-resource settings despite
being preventable through human papillomavirus (HPV) vaccination, early detection, and …

Evaluation of an Isothermal amplification HPV assay on self-collected vaginal samples as compared to clinician-collected cervical samples

AHY Chan, SF Ngu, LSK Lau, OKL Tsun, HYS Ngan… - Diagnostics, 2023 - mdpi.com
This study aimed to evaluate the concordance of HPV results between the SentisTM HPV
assay (Sentis)(BGI Group, Shenzhen, China), an isothermal amplification-based HPV assay …

A multiplexed, allele-specific recombinase polymerase amplification assay with lateral flow readout for sickle cell disease detection

MM Chang, ME Natoli, AF Wilkinson, VN Tubman… - Lab on a Chip, 2024 - pubs.rsc.org
Isothermal nucleic acid amplification tests have the potential to improve disease diagnosis at
the point of care, but it remains challenging to develop multiplexed tests that can detect≥ 3 …

Advanced technologies towards improved HPV diagnostics

M Bartosik, L Moranova, N Izadi… - Journal of Medical …, 2024 - Wiley Online Library
Persistent infection with high‐risk types of human papillomaviruses (HPV) is a major cause
of cervical cancer, and an important factor in other malignancies, for example, head and …

Sensitive, Semiquantitative, and Portable Nucleic Acid Detection of Rabies Virus Using a Personal Glucose Meter

J Lu, Y Bai, X Wang, P Huang, M Liu, R Wang… - ACS …, 2024 - ACS Publications
Rabies is a zoonotic infection with the potential to infect all mammals and poses a significant
threat to mortality. Although enzyme-linked immunosorbent tests and real-time reverse …