Interleukin-1β and cancer
C Rébé, F Ghiringhelli - Cancers, 2020 - mdpi.com
Within a tumor, IL-1β is produced and secreted by various cell types, such as immune cells,
fibroblasts, or cancer cells. The IL1B gene is induced after “priming” of the cells and a …
fibroblasts, or cancer cells. The IL1B gene is induced after “priming” of the cells and a …
Prostate carcinogenesis: inflammatory storms
Prostate cancer is a major cause of cancer morbidity and mortality. Intra-prostatic
inflammation is a risk factor for prostate carcinogenesis, with diet, chemical injury and an …
inflammation is a risk factor for prostate carcinogenesis, with diet, chemical injury and an …
Blocking IL1 beta promotes tumor regression and remodeling of the myeloid compartment in a renal cell carcinoma model: multidimensional analyses
Purpose: Intratumoral immunosuppression mediated by myeloid-derived suppressor cells
(MDSC) and tumor-associated macrophages (TAM) represents a potential mechanism of …
(MDSC) and tumor-associated macrophages (TAM) represents a potential mechanism of …
IL8 expression is associated with prostate cancer aggressiveness and androgen receptor loss in primary and metastatic prostate cancer
Chronic inflammation and African ancestry are implicated in prostate cancer
aggressiveness, and inflammation-related genes are more highly expressed in prostate …
aggressiveness, and inflammation-related genes are more highly expressed in prostate …
Health inequity drives disease biology to create disparities in prostate cancer outcomes
Prostate cancer exerts a greater toll on African American men than on White men of
European descent (hereafter referred to as European American men): the disparity in …
European descent (hereafter referred to as European American men): the disparity in …
Chemokines and cytokines: Axis and allies in prostate cancer pathogenesis
Chemokines are recognized as the major contributor to various tumorigenesis, tumor
heterogeneity, and failures of current cancer therapies. The tumor microenvironment (TME) …
heterogeneity, and failures of current cancer therapies. The tumor microenvironment (TME) …
Autonomic nervous system dysfunction is related to chronic prostatitis/chronic pelvic pain syndrome
H He, H Luo, B Qian, H Xu, G Zhang… - The World Journal of …, 2023 - pmc.ncbi.nlm.nih.gov
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a common and non-lethal
urological condition with painful symptoms. The complexity of CP/CPPS's pathogenesis and …
urological condition with painful symptoms. The complexity of CP/CPPS's pathogenesis and …
Trinity of inflammation, innate immune cells and cross-talk of signalling pathways in tumour microenvironment
Unresolved inflammation is a pathological consequence of persistent inflammatory stimulus
and perturbation in regulatory mechanisms. It increases the risk of tumour development and …
and perturbation in regulatory mechanisms. It increases the risk of tumour development and …
Protocatechuic acid ameliorates testosterone‐induced benign prostatic hyperplasia through the regulation of inflammation and oxidative stress in castrated rats
Protocatechuic acid (PA) is a polyphenol—recognized for its efficacy as an antioxidant—
possesses anticancer, anti‐inflammatory, antioxidant properties. The efficacy of PA in the …
possesses anticancer, anti‐inflammatory, antioxidant properties. The efficacy of PA in the …
Single‐cell atlas of epithelial and stromal cell heterogeneity by lobe and strain in the mouse prostate
Background Evaluating the complex interplay of cell types in the tissue microenvironment is
critical to understanding the origin and progression of diseases in the prostate and potential …
critical to understanding the origin and progression of diseases in the prostate and potential …