Recent advancement in understanding of Alzheimer's disease: Risk factors, subtypes, and drug targets and potential therapeutics

S Prabha, M Sajad, GM Hasan, A Islam… - Ageing Research …, 2024 - Elsevier
Alzheimer's disease (AD) is a significant neocortical degenerative disorder characterized by
the progressive loss of neurons and secondary alterations in white matter tracts …

Outcome over seven years of healthy adults with and without subjective cognitive impairment

B Reisberg, MB Shulman, C Torossian, L Leng… - Alzheimer's & …, 2010 - Elsevier
BACKGROUND: Subjective cognitive impairment (SCI) in older persons without manifest
symptomatology is a common condition with a largely unclear prognosis. We hypothesized …

Incidence and outcome of mild cognitive impairment in a population-based prospective cohort

S Larrieu, L Letenneur, JM Orgogozo, C Fabrigoule… - Neurology, 2002 - AAN Enterprises
Objective: To estimate the age-specific incidence rate of mild cognitive impairment (MCI)
according to sex and educational level and to explore the course of MCI, particularly its …

The BEHAVE-AD assessment system: a perspective, a commentary on new findings, and a historical review

B Reisberg, I Monteiro, C Torossian, S Auer… - Dementia and geriatric …, 2014 - karger.com
Background: Behavioral and psychological symptoms of dementia (BPSD) and associated
disturbances in Alzheimer's disease (AD) are a source of distress and burden for spouses …

The GDS/FAST staging system

S Auer, B Reisberg - International Psychogeriatrics, 1997 - cambridge.org
Staging methodologies are an essential tool in the assessment of disease severity in
progressive dementing illness. Several different instruments have been developed for this …

Equilibrium and limb coordination in mild cognitive impairment and mild Alzheimer's disease

EH Franssen, LEM Somen… - Journal of the …, 1999 - Wiley Online Library
OBJECTIVE: To examine changes in equilibrium and limb coordination in normal aging,
mild cognitive impairment, and moderate cognitive impairment associated with early …

Subjective memory complaints: presence, severity and future outcome in normal older subjects

L Glodzik-Sobanska, B Reisberg, S De Santi… - Dementia and geriatric …, 2007 - karger.com
Abstract Background/Aims: Subjective memory complaint (SMC) in normal individuals may
predict future cognitive decline. The goal of this study was to examine whether the …

[图书][B] The aging individual: Physical and psychological perspectives

SK Whitbourne - 2002 - books.google.com
Continuing in the tradition of the first edition, Whitbourneís identity process model serves to
integrate the physiological with a psychological perspective. The effects of physical changes …

Global measures: utility in defining and measuring treatment response in dementia

B Reisberg - International Psychogeriatrics, 2007 - cambridge.org
Global measures used in treatment trials in dementia encompass two distinct categories:(1)
clinician's interview-based global severity scales, and (2) clinician's interview-based global …

[图书][B] Clinical geriatric psychopharmacology

C Salzman - 2005 - books.google.com
Thoroughly updated for its Fourth Edition, this volume is the most authoritative clinical
reference on the pharmacologic treatment of psychiatric disorders in elderly patients. This …