Chalcone is a unique template that is associated with several biological activities. In this
review, an update of the cytotoxic and chemoprotective activities of chalcones is provided …

Chalcones are a group of plant-derived polyphenolic compounds belonging to the
flavonoids family and possess a wide variety of cytoprotective and modulatory functions. The …

Electrooxidative-induced synthesis of structurally diverse seleno-dibenzocyclohepten-5-
ones and seleno-spiro [5.5] trienones by selenylative carbannulation of biaryl ynones with …

A series of ferrocenyl chalcones were synthesized and evaluated in vitro against
Plasmodium falciparum (K1) in a [3H] hypoxanthine uptake assay. Appropriate size …

As flavonoids, chalcones possess a wide variety of biological activities including anticancer
properties. In the present study we have investigated the in vitro antiproliferative and …

A series of E-2-quinolinylbenzocycloalcanones 5–21 were prepared and evaluated for their
activity to inhibit β-hematin formation and the hydrolysis of hemoglobin in vitro. Positive …

Introduction: Imidazothiazole derivatives have long been therapeutically used for the
treatment of various diseases. In recent years, the imidazothiazole and chalcone moieties …

A series of 3-benzylidene-4-chromanones 1a–l were prepared and their cytotoxicity towards
human Molt 4/C8 and CEM T-lymphocytes as well as murine L1210 lymphoid leukemia cells …

Non-enzymatic thiol addition into the α, β-unsaturated carbonyl system is associated with
several biological effects. In vivo, the reactions can form small-molecule thiol (eg …

Aims Chalcones, naturally occurring open-chain polyphenols abundant in plants, have
demonstrated antiproliferative activity in several cancer cell lines. In the present study, the …