Triazoles are important five-membered heterocyclic scaffold due to their extensive biological
activities. This framework can be readily obtained in good to excellent yields on the …

The reactions of organic azides and alkynes catalysed by copper species represent the
prototypical examples of click chemistry. The so-called CuAAC reaction (copper-catalysed …

Chemistry, traditionally being the science of synthesis and structural manipulations of
molecules, has gradually undertaken the more challenging task of biology-oriented …

Abstract The copper (I)‐catalyzed 1, 2, 3‐triazole‐forming reaction between azides and
terminal alkynes has become the gold standard of 'click chemistry'due to its reliability …

A short overview of the copper (I)-catalyzed azide alkyne cycloaddition (CuAAC), the most
used “click” reaction, is presented, including the introduction of the “click” concept, the …

The Huisgen 1, 3-dipolar cycloaddition reaction of organic azides and alkynes1, 2 has
gained considerable attention in recent years due to the introduction in 2001 of Cu (1) …

Transition metal catalyzed denitrogenative transannulation of a triazole ring has recently
received considerable attention as a new concept for the construction of diverse nitrogen …

In recent years, there has been an ever‐increasing need for rapid reactions that meet the
three main criteria of an ideal synthesis: efficiency, versatility, and selectivity. Such reactions …

CuI‐catalyzed alkyne–azide cycloaddition provides 1, 4‐disubstituted 1, 2, 3‐triazoles with
such efficiency and scope that the transformation has been described as “click” chemistry …

The investigation of biological processes by chemical methods, commonly referred to as
chemical biology, often requires chemical access to biologically relevant macromolecules …