Growth-associated protein-43 (GAP-43) and brain acid-soluble protein 1 (BASP1) regulate
actin dynamics and presynaptic vesicle cycling at axon terminals, thereby facilitating axonal …

Several lines of investigation have helped clarify the role of GAP-43 (F1, B-50 or
neuromodulin) in regulating the growth state of axon terminals. In transgenic mice …

Axon regeneration in the CNS is inhibited by many extrinsic and intrinsic factors. Because
these act in parallel, no single intervention has been sufficient to enable full regeneration of …

In a number of animal species, the growth-associated protein (GAP), GAP-43 (aka: F1,
neuromodulin, B-50, G50, pp46), has been implicated in the regulation of presynaptic …

For nerve cells to develop their highly polarized form, appropriate structural molecules must
be targeted to either axons or dendrites. This could be achieved by the synthesis of …

ABSTRACT Cyclin-dependent kinase 5 (cdk5) was originally isolated on the basis of its
close primary sequence homology to the human cdc2 serine/threonine kinase, the prototype …

The locus elav (ella-vee) of Drosophila melanogaster, which is necessary for the proper
development of the embryonic and adult nervous systems, has been characterized both …

The complete absence of leptin causes severe obesity in mice and humans, but its
physiological roles are incompletely defined. Earlier studies reported decreased brain …

This is the first book on the neurobiology of learning and memory that covers
comprehensively all levels of analysis, from molecules to brain, in both invertebrates and …

Growth cones are specialized structures that form the distal tips of growing axons. During
both normal development of the nervous system and regeneration of injured nerves, growth …