GAP-43 and BASP1 in axon regeneration: implications for the treatment of neurodegenerative diseases
D Chung, A Shum, G Caraveo - Frontiers in cell and developmental …, 2020 - frontiersin.org
Growth-associated protein-43 (GAP-43) and brain acid-soluble protein 1 (BASP1) regulate
actin dynamics and presynaptic vesicle cycling at axon terminals, thereby facilitating axonal …
actin dynamics and presynaptic vesicle cycling at axon terminals, thereby facilitating axonal …
GAP-43: an intrinsic determinant of neuronal development and plasticity
LI Benowitz, A Routtenberg - Trends in neurosciences, 1997 - cell.com
Several lines of investigation have helped clarify the role of GAP-43 (F1, B-50 or
neuromodulin) in regulating the growth state of axon terminals. In transgenic mice …
neuromodulin) in regulating the growth state of axon terminals. In transgenic mice …
The struggle to make CNS axons regenerate: why has it been so difficult?
JW Fawcett - Neurochemical research, 2020 - Springer
Axon regeneration in the CNS is inhibited by many extrinsic and intrinsic factors. Because
these act in parallel, no single intervention has been sufficient to enable full regeneration of …
these act in parallel, no single intervention has been sufficient to enable full regeneration of …
A shift from a pivotal to supporting role for the growth-associated protein (GAP-43) in the coordination of axonal structural and functional plasticity
MR Holahan - Frontiers in Cellular Neuroscience, 2017 - frontiersin.org
In a number of animal species, the growth-associated protein (GAP), GAP-43 (aka: F1,
neuromodulin, B-50, G50, pp46), has been implicated in the regulation of presynaptic …
neuromodulin, B-50, G50, pp46), has been implicated in the regulation of presynaptic …
Selective localization of messenger RNA for cytoskeletal protein MAP2 in dendrites
CC Garner, RP Tucker, A Matus - Nature, 1988 - nature.com
For nerve cells to develop their highly polarized form, appropriate structural molecules must
be targeted to either axons or dendrites. This could be achieved by the synthesis of …
be targeted to either axons or dendrites. This could be achieved by the synthesis of …
Activity and expression pattern of cyclin-dependent kinase 5 in the embryonic mouse nervous system
LH Tsai, T Takahashi, VS Caviness Jr… - …, 1993 - journals.biologists.com
ABSTRACT Cyclin-dependent kinase 5 (cdk5) was originally isolated on the basis of its
close primary sequence homology to the human cdc2 serine/threonine kinase, the prototype …
close primary sequence homology to the human cdc2 serine/threonine kinase, the prototype …
The locus elav of Drosophila melanogaster is expressed in neurons at all developmental stages
S Robinow, K White - Developmental biology, 1988 - Elsevier
The locus elav (ella-vee) of Drosophila melanogaster, which is necessary for the proper
development of the embryonic and adult nervous systems, has been characterized both …
development of the embryonic and adult nervous systems, has been characterized both …
Regulation of neuronal and glial proteins by leptin: implications for brain development
The complete absence of leptin causes severe obesity in mice and humans, but its
physiological roles are incompletely defined. Earlier studies reported decreased brain …
physiological roles are incompletely defined. Earlier studies reported decreased brain …
[图书][B] The neurobiology of memory: concepts, findings, trends.
Y Dudai - 1989 - psycnet.apa.org
This is the first book on the neurobiology of learning and memory that covers
comprehensively all levels of analysis, from molecules to brain, in both invertebrates and …
comprehensively all levels of analysis, from molecules to brain, in both invertebrates and …
A protein induced during nerve growth (GAP-43) is a major component of growth-cone membranes
JHP Skene, RD Jacobson, GJ Snipes, CB McGuire… - Science, 1986 - science.org
Growth cones are specialized structures that form the distal tips of growing axons. During
both normal development of the nervous system and regeneration of injured nerves, growth …
both normal development of the nervous system and regeneration of injured nerves, growth …