Objective This narrative review aims to update the reader on the new classification of
trigeminal neuralgia (TN), clinical signs, pathophysiologic evidence, and their implications …

Trigeminal neuralgia (TN) is a severe facial pain disease of unknown cause and unclear
genetic background. To examine the existing knowledge about genetics in TN, we …

Objective This cross-sectional study examined, for the first time, a large cohort of patients
with trigeminal neuralgia, to ascertain the occurrence of familial cases, providing a …

Trigeminal neuralgia (TN) is a unique pain disorder characterized by intense paroxysmal
facial pain within areas innervated by the trigeminal nerve. Although most cases of TN are …

Objective To conduct a systematic review of the available literature for primary research
articles identifying potential gene mutations, polymorphisms and other molecular regulatory …

Objective This study aimed to characterize key features, and to assess the clinical
development of common nondental facial pain syndromes such as persistent idiopathic …

Background Trigeminal neuralgia is characterized by pain at the distribution of one or more
of the trigeminal nerve branches and is usually treated with anti-epileptic medication. When …

In this review, we will explore the use of biomarkers in chronic pain, using the examples of
two prototypical facial pain conditions: trigeminal neuralgia and temporomandibular …

Trigeminal neuralgia (TN) is a facial pain disorder characterized by intense and paroxysmal
pain that profoundly affects quality of life and presents complex challenges in diagnosis and …

Objective To assess the functional effects of a variant, c. 89 G> A (p. Arg30Gln), in the
transient receptor potential melastatin 8 (TRPM8) cold-sensing, nonselective cation channel …