Characterization of the type I restriction modification system broadly conserved among group A streptococci
Although prokaryotic DNA methylation investigations have long focused on immunity against
exogenous DNA, it has been recently recognized that DNA methylation impacts gene …
exogenous DNA, it has been recently recognized that DNA methylation impacts gene …
Epigenetic regulation alters biofilm architecture and composition in multiple clinical isolates of nontypeable Haemophilus influenzae
KL Brockman, PN Azzari, MT Branstool, JM Atack… - MBio, 2018 - Am Soc Microbiol
Biofilms play a critical role in the colonization, persistence, and pathogenesis of many
human pathogens. Multiple mucosa-associated pathogens have evolved a mechanism of …
human pathogens. Multiple mucosa-associated pathogens have evolved a mechanism of …
DNA methylation in prokaryotes
J Casadesús, MA Sánchez-Romero - DNA Methyltransferases-Role and …, 2022 - Springer
The genomes of bacteria, archaea, and phage contain small amounts of C5-methylcytosine,
N4-methylcytosine, and N6-methyladenine. Base methylation takes place after DNA …
N4-methylcytosine, and N6-methyladenine. Base methylation takes place after DNA …
Adherence of nontypeable haemophilus influenzae to cells and substrates of the airway is differentially regulated by individual modA phasevarions
Adherence of nontypeable Haemophilus influenzae (NTHi) to the host airway is an essential
initial step for asymptomatic colonization of the nasopharynx, as well as development of …
initial step for asymptomatic colonization of the nasopharynx, as well as development of …
Methylomic and phenotypic analysis of the ModH5 phasevarion of Helicobacter pylori
The Helicobacter pylori phase variable gene modH, typified by gene HP1522 in strain
26695, encodes a N6-adenosine type III DNA methyltransferase. Our previous studies …
26695, encodes a N6-adenosine type III DNA methyltransferase. Our previous studies …
Systematic Analysis of REBASE Identifies Numerous Type I Restriction-Modification Systems with Duplicated, Distinct hsdS Specificity Genes That Can Switch …
ABSTRACT N 6-Adenine DNA methyltransferases associated with some Type I and Type III
restriction-modification (RM) systems are able to undergo phase variation, randomly …
restriction-modification (RM) systems are able to undergo phase variation, randomly …
Comparative genomics reveals the diversity of restriction-modification systems and DNA methylation sites in Listeria monocytogenes
P Chen, HC den Bakker, J Korlach… - Applied and …, 2017 - Am Soc Microbiol
Listeria monocytogenes is a bacterial pathogen that is found in a wide variety of
anthropogenic and natural environments. Genome sequencing technologies are rapidly …
anthropogenic and natural environments. Genome sequencing technologies are rapidly …
Phase variation in HMW1A controls a phenotypic switch in Haemophilus influenzae associated with pathoadaptation during persistent infection
A Fernández-Calvet, B Euba, C Gil-Campillo… - Mbio, 2021 - Am Soc Microbiol
Genetic variants arising from within-patient evolution shed light on bacterial adaptation
during chronic infection. Contingency loci generate high levels of genetic variation in …
during chronic infection. Contingency loci generate high levels of genetic variation in …
Identification of a DNA-cytosine methyltransferase that impacts global transcription to promote group B streptococcal vaginal colonization
HS Manzer, T Brunetti, KS Doran - Mbio, 2023 - Am Soc Microbiol
ABSTRACT Group B Streptococcus (GBS) colonizes the female reproductive tract (FRT) and
causes adverse pregnancy outcomes and invasive disease following vertical transmission to …
causes adverse pregnancy outcomes and invasive disease following vertical transmission to …
Streptococcus suis encodes multiple allelic variants of a phase-variable Type III DNA methyltransferase, ModS, that control distinct phasevarions
G Tram, FEC Jen, ZN Phillips, J Timms, AU Husna… - Msphere, 2021 - Am Soc Microbiol
Streptococcus suis is a significant cause of bacterial meningitis in humans, particularly in
Southeast Asia, and is a leading cause of respiratory and invasive disease in pigs. Phase …
Southeast Asia, and is a leading cause of respiratory and invasive disease in pigs. Phase …