Primary malignant bone tumors are rare sarcomas with an estimated frequency of about
2900 new cases per year; they constitute less than 0.2% of all cancers diagnosed in the …

The availability of high-fidelity animal models for oncology research has grown enormously
in recent years, enabling preclinical studies relevant to prevention, diagnosis, and treatment …

Ferulic acid, a ubiquitous phenolic acid abundant in corn, wheat and flax, has potent anti-
tumor effect in various cancer cell lines. However, the anti-tumor effect of ferulic acid on …

Osteosarcoma is the most common primary bone tumor characterized by juvenile onset,
tumor heterogeneity, and early pulmonary metastasis. Therapeutic improvement stagnates …

OBJECTIVE. The purpose of this study was to compare the diagnostic performance of 18F-
FDG PET/CT and conventional imaging for staging and follow-up of pediatric osteosarcoma …

Purpose The aims of this study were to determine the effect of curcumin on osteosarcoma
(OS) cells due to inactivation of the p-JAK2/p-STAT3 pathway and evaluate the prognostic …

Osteosarcoma is the most prevalent primary malignant bone tumor mainly endangering
young adults. In this study, we explore whether polydatin (PD), a glycoside form of …

Intratumoral hypoxia occurs in many solid tumors, where it is associated with the
development of metastatic character. However, the connections between these phenomena …

Abstract Background and Objectives Fibroblast activation protein (FAP) expression has
been detected in fibroblastic component of osteosarcomas. The aim of this study was to …

Background: Nowadays it remains a controversial issue whether a correlation exists
between the apoptosis rate of tumor tissue and the prognosis of the patients. The aim of the …