Protein corona: a new approach for nanomedicine design
After administration of nanoparticle (NP) into biological fluids, an NP–protein complex is
formed, which represents the “true identity” of NP in our body. Hence, protein–NP interaction …
formed, which represents the “true identity” of NP in our body. Hence, protein–NP interaction …
Nanoparticle uptake: the phagocyte problem
HH Gustafson, D Holt-Casper, DW Grainger… - Nano today, 2015 - Elsevier
Phagocytes are key cellular participants determining important aspects of host exposure to
nanomaterials, initiating clearance, biodistribution and the tenuous balance between host …
nanomaterials, initiating clearance, biodistribution and the tenuous balance between host …
Antibiofouling polymer interfaces: poly (ethylene glycol) and other promising candidates
Nonspecific protein adsorption and/or microbial adsorption on biomedical materials
adversely affects the efficacy of a range of biomedical systems, from implants and …
adversely affects the efficacy of a range of biomedical systems, from implants and …
Physicochemical characteristics of nanoparticles affect circulation, biodistribution, cellular internalization, and trafficking
X Duan, Y Li - Small, 2013 - Wiley Online Library
Nanoparticles have many potential applications in tumor therapy. Systemically administered
nanoparticles should remain in circulation for a long time to increase their accumulation in …
nanoparticles should remain in circulation for a long time to increase their accumulation in …
Recent strategies and advances in the fabrication of nano lipid carriers and their application towards brain targeting
In last two decades, the lipid nanocarriers have been extensively investigated for their drug
targeting efficiency towards the critical areas of the human body like CNS, cardiac region …
targeting efficiency towards the critical areas of the human body like CNS, cardiac region …
The effect of surface charge on in vivo biodistribution of PEG-oligocholic acid based micellar nanoparticles
To systematically elucidate the effect of surface charge on the cellular uptake and in vivo fate
of PEG-oligocholic acid based micellar nanoparticles (NPs), the distal PEG termini of …
of PEG-oligocholic acid based micellar nanoparticles (NPs), the distal PEG termini of …
The journey of a drug-carrier in the body: an anatomo-physiological perspective
N Bertrand, JC Leroux - Journal of controlled release, 2012 - Elsevier
Recent advances in chemistry and material sciences have witnessed the emergence of an
increasing number of novel and complex nanosized carriers for the delivery of drugs and …
increasing number of novel and complex nanosized carriers for the delivery of drugs and …
Magnetic iron oxide nanoparticles as drug carriers: clinical relevance
K El-Boubbou - Nanomedicine, 2018 - Taylor & Francis
Significant preclinical and clinical research has explored the use of magnetic iron oxide
nanoparticles (MNPs) for medical theranostics. Herein, we provide an overview of the …
nanoparticles (MNPs) for medical theranostics. Herein, we provide an overview of the …
Biopolymer-based microgels/nanogels for drug delivery applications
JK Oh, DI Lee, JM Park - Progress in polymer science, 2009 - Elsevier
Polysaccharide-based microgels/nanogels have high water content, functionality,
biocompatibility, tunable size from submicrons to tens of nanometers, large surface area for …
biocompatibility, tunable size from submicrons to tens of nanometers, large surface area for …
Nanoparticle–protein corona complexes govern the biological fates and functions of nanoparticles
Upon contact with plasma or other protein-containing biological fluids, the surface of
nanoparticles is immediately decorated with proteins forming a biologically active protein …
nanoparticles is immediately decorated with proteins forming a biologically active protein …