Importance Pituitary adenomas may hypersecrete hormones or cause mass effects.
Therefore, early diagnosis and treatment are important. Observations Prevalence of pituitary …

Acromegaly is a chronic systemic disease with many complications and is associated with
increased mortality when not adequately treated. Substantial advances in acromegaly …

Objective The aim of the Acromegaly Consensus Group was to revise and update the
consensus on diagnosis and treatment of acromegaly comorbidities last published in 2013 …

Objective: The aim was to formulate clinical practice guidelines for acromegaly. Participants:
The Task Force included a chair selected by the Endocrine Society Clinical Guidelines …

Background Acromegaly is a rare and underdiagnosed disorder caused, in more than 95%
of cases, by a growth hormone (GH)-secreting pituitary adenoma. The GH hypersecretion …

Circulating insulin-like growth factor I (IGF-I) is positively associated with the risks of
colorectal, breast, and prostate cancer, but evidence for other less common cancers is …

Acromegaly is caused by excess growth hormone (GH) secretion emanating from a
somatotroph adenoma. High GH and Insulin-like growth factor-1 (IGF-1) levels lead to acral …

Acromegaly (ACM) is a chronic, progressive disorder caused by the persistent
hypersecretion of GH, in the vast majority of cases secreted by a pituitary adenoma. The …

Context: GH and IGF-1 have been shown to affect tumor growth in vitro and in some animal
models. This report summarizes the available evidence on whether GH therapy in childhood …

Based on experimental and animal models, epidemiological data from non-acromegaly
populations, and longitudinal and cross-sectional cohorts of patients with acromegaly, a …