Multiscale modeling of the neuromuscular system: coupling neurophysiology and skeletal muscle mechanics

O Röhrle, UŞ Yavuz, T Klotz, F Negro… - … : Systems Biology and …, 2019 - Wiley Online Library
Mathematical models and computer simulations have the great potential to substantially
increase our understanding of the biophysical behavior of the neuromuscular system. This …

[HTML][HTML] Skeletal muscle models composed of motor units: A review

R Raikova, P Krutki, J Celichowski - Journal of Electromyography and …, 2023 - Elsevier
The mathematical muscle models should include several aspects of muscle structure and
physiology. First, muscle force is the sum of forces of multiple motor units (MUs), which have …

The effective neural drive to muscles is the common synaptic input to motor neurons

D Farina, F Negro, JL Dideriksen - The Journal of physiology, 2014 - Wiley Online Library
Key points Despite the non‐linear property of individual motor neurons, the pool of motor
neurons linearizes the relation between their common synaptic input and the neural drive to …

Spinal mechanisms may provide a combination of intermittent and continuous control of human posture: predictions from a biologically based neuromusculoskeletal …

LA Elias, RN Watanabe, AF Kohn - PLoS computational biology, 2014 - journals.plos.org
Several models have been employed to study human postural control during upright quiet
stance. Most have adopted an inverted pendulum approximation to the standing human and …

Fast oscillatory commands from the motor cortex can be decoded by the spinal cord for force control

RN Watanabe, AF Kohn - Journal of Neuroscience, 2015 - Soc Neuroscience
Oscillations in the beta and gamma bands (13–30 Hz; 35–70 Hz) have often been observed
in motor cortical outputs that reach the spinal cord, acting on motoneurons and interneurons …

Sex steroids as regulators of gestural communication

DJ Tobiansky, MJ Fuxjager - Endocrinology, 2020 - academic.oup.com
Gestural communication is ubiquitous throughout the animal kingdom, occurring in species
that range from humans to arthropods. Individuals produce gestural signals when their …

Influences of premotoneuronal command statistics on the scaling of motor output variability during isometric plantar flexion

RN Watanabe, FH Magalhães… - Journal of …, 2013 - journals.physiology.org
This study focuses on neuromuscular mechanisms behind ankle torque and EMG variability
during a maintained isometric plantar flexion contraction. Experimentally obtained torque …

Effects of voluntary contraction on the soleus H-reflex of different amplitudes in healthy young adults and in the elderly

L Batista-Ferreira, NF Rabelo, GM Cruz… - Frontiers in human …, 2022 - frontiersin.org
A number of H-reflex studies used a moderate steady voluntary contraction in an attempt to
keep the motoneuron pool excitability relatively constant. However, it is not clear whether the …

Experimental and simulated EMG responses in the study of the human spinal cord

RA Mezzarane, LA Elias, FH Magalhães… - … in new frontiers of …, 2013 - books.google.com
Advances in the study of human spinal cord neurophysiology have been strongly based on
the analysis of the electrical activity of muscles (electromyogram-EMG). The EMG measured …

Personalized alpha-motoneuron pool models driven by neural data encode the mechanisms controlling rate of force development

R Ornelas-Kobayashi, I Gomez-Orozco… - … on Neural Systems …, 2024 - ieeexplore.ieee.org
The central nervous system employs distinct motor control strategies depending on task
demands. Accordingly, the activity of alpha-motoneuron (MN) pools innervating skeletal …