Endometrial function in women with polycystic ovary syndrome: a comprehensive review

S Palomba, TT Piltonen… - Human reproduction …, 2021 - academic.oup.com
BACKGROUND Polycystic ovary syndrome (PCOS) is the most common cause of
anovulatory infertility. An endometrial component has been suggested to contribute to …

Estrogen-receptor expression and function in female reproductive disease

ZR Tang, R Zhang, ZX Lian, SL Deng, K Yu - Cells, 2019 - mdpi.com
Estrogen receptors (ER) include ER alpha, ER beta and new membrane receptor G protein-
coupled receptor 30 (GPR30). Estrogen receptors are key receptors to maintain ovarian …

Cancer risk and PCOS

DA Dumesic, RA Lobo - Steroids, 2013 - Elsevier
Women with polycystic ovary syndrome (PCOS) have a 2.7-fold increased risk for
developing endometrial cancer. A major factor for this increased malignancy risk is …

Estrogen biosynthesis and signal transduction in ovarian disease

XL Xu, ZY Huang, K Yu, J Li, XW Fu… - Frontiers in …, 2022 - frontiersin.org
Estrogen mainly binds to estrogen receptors (ERs) to regulate menstrual cycles and
reproduction. The expression of ERalpha (ERα), ERbeta (ERβ), and G-protein-coupled …

Endometrial progesterone resistance and PCOS

X Li, Y Feng, JF Lin, H Billig, R Shao - Journal of biomedical science, 2014 - Springer
Polycystic ovary syndrome (PCOS) is a state of altered steroid hormone production and
activity. Chronic estrogen exposure or lack of progesterone due to ovarian dysfunction can …

Polycystic ovary syndrome: endometrial markers

TT Piltonen - Best practice & research Clinical obstetrics & …, 2016 - Elsevier
Women with polycystic ovarian syndrome (PCOS) present with several endometrial
abnormalities possibly explaining some of the adverse endometrium-related outcomes in …

Associations between insulin resistance, free fatty acids, and oocyte quality in polycystic ovary syndrome during in vitro fertilization

Z Niu, N Lin, R Gu, Y Sun, Y Feng - The Journal of Clinical …, 2014 - academic.oup.com
Context: Both polycystic ovary syndrome (PCOS) and obesity are associated with specific
reproductive health complications, including lower oocyte quality and clinical pregnancy …

Integrative analyses of uterine transcriptome and microRNAome reveal compromised LIF-STAT3 signaling and progesterone response in the endometrium of patients …

Y Choi, HR Kim, EJ Lim, M Park, JA Yoon, YS Kim… - PloS one, 2016 - journals.plos.org
Intimate two-way interactions between the implantation-competent blastocyst and receptive
uterus are prerequisite for successful embryo implantation. In humans, recurrent/repeated …

Warburg-like glycolysis and lactate shuttle in mouse decidua during early pregnancy

RJ Zuo, XW Gu, QR Qi, TS Wang, XY Zhao… - Journal of Biological …, 2015 - ASBMB
Decidualization is an essential process of maternal endometrial stromal cells to support
pregnancy. Although it is known that enhanced glucose influx is critical for decidualization …

Inflammatory stimuli trigger increased androgen production and shifts in gene expression in theca-interstitial cells

CW Fox, L Zhang, A Sohni, M Doblado… - …, 2019 - academic.oup.com
Polycystic ovary syndrome (PCOS) is a common reproductive endocrine disorder
characterized by theca cell hyperplasia and excessive androgen production. An increasing …