Thiazolidin-4-one scaffold has great potential for medicinal chemistry and is of interest to
scientists in view of wide spectrum of biological activity. This scaffold is often used for …

The Chemo- and Regioselectivity of the Cyclization of Thiosemicarbazides with Haloacetic Acids
and their Derivatives | Chemistry of Heterocyclic Compounds Skip to main content SpringerLink …

Thiazolidinones and phenylaminopyrimidines are known as anticancer agents. Imatinib is
the pioneer phenylaminopyrimidine derivative kinase inhibitor, which is used for the …

Abstract Hepatitis C virus (HCV) NS5B polymerase is an important and attractive target for
the development of anti-HCV drugs. Here we report on the design, synthesis and evaluation …

In continuation of our efforts to develop new derivatives as hepatitis C virus (HCV) NS5B
inhibitors, we synthesized novel 5‐arylidene‐4‐thiazolidinones. The novel compounds 29 …

A novel series of new flurbiprofen hydrazide derivatives 2-(2-fluorobiphenyl-4-yl)-N′-
[(substituted phenyl/5-nitro-2-furyl) methylene] propanehydrazide (3a–k), 2-(2-fluorobiphenyl …

Hepatitis C (HCV) is a viral infection that leads to forms of acute and chronic liver disease,
including cirrhosis (scarring of the liver) and liver cancer. The World Health Organization …

Mycobacteria regulate the synthesis of mycolic acid through the fatty acid synthase system
type 1 (FAS I) and the fatty acid synthase system type-2 (FAS-II). Because mammalian cells …

1, 3-Thiazolidine-4-ones have been known to possess anti-HIV and anti-HCV activity as they
are, respectively, HIV-1 non-nucleoside reverse transcriptase inhibitors and HCV NS5B …

Abstract In this study, new 1, 3-thiazolidin-4-one derivatives containing arylmethylene
groups in the 5-position were obtained from 6-(trifluoromethoxy)-1, 3-benzothiazol-2-amine …