Mesenchymal stem/stromal cell-derived exosomes for immunomodulatory therapeutics and skin regeneration

DH Ha, H Kim, J Lee, HH Kwon, GH Park, SH Yang… - Cells, 2020 - mdpi.com
Exosomes are nano-sized vesicles that serve as mediators for cell-to-cell communication.
With their unique nucleic acids, proteins, and lipids cargo compositions that reflect the …

Exosomes from adipose-derived stem cells: the emerging roles and applications in tissue regeneration of plastic and cosmetic surgery

M Xiong, Q Zhang, W Hu, C Zhao, W Lv, Y Yi… - Frontiers in Cell and …, 2020 - frontiersin.org
Adipose-derived stem cells (ASCs) are an important stem cell type separated from adipose
tissue, with the properties of multilineage differentiation, easy availability, high proliferation …

Advances in lncRNAs from stem cell-derived exosome for the treatment of cardiovascular diseases

J Ma, P Lei, H Chen, L Wang, Y Fang, X Yan… - Frontiers in …, 2022 - frontiersin.org
Cardiovascular diseases (CVDs) are the leading cause of mortality globally. Benefiting from
the advantages of early diagnosis and precision medicine, stem cell-based therapies have …

[HTML][HTML] Adipose-derived stem cells applied in skin diseases, wound healing and skin defects: a review

I Schneider, M Calcagni, J Buschmann - Cytotherapy, 2023 - Elsevier
Adipose tissue presents a comparably easy source for obtaining stem cells, and more
studies are increasingly investigating the therapeutic potential of adipose-derived stem cells …

Adipose-derived stem cell secretome as a cell-free product for cutaneous wound healing

A Ajit, I Ambika Gopalankutty - 3 Biotech, 2021 - Springer
Chronic wounds continue to be a substantial public health concern contributing to both
humanistic and economic burden worldwide. The magnitude of chronic wounds as a global …

Development of secretome-based strategies to improve cell culture protocols in tissue engineering

O Cases-Perera, C Blanco-Elices, J Chato-Astrain… - Scientific reports, 2022 - nature.com
Advances in skin tissue engineering have promoted the development of artificial skin
substitutes to treat large burns and other major skin loss conditions. However, one of the …

A novel variant in TAF1 affects gene expression and is associated with X-linked TAF1 intellectual disability syndrome

SE Hurst, E Liktor-Busa, A Moutal, S Parker… - Neuronal …, 2018 - portlandpress.com
We investigated the genome of a 5-year-old male who presented with global developmental
delay (motor, cognitive, and speech), hypotonia, possibly ataxia, and cerebellar hypoplasia …

Neuroprotection of retinal ganglion cells in vivo using the activation of the endogenous cannabinoid signaling system in mammalian eyes

G Maguire, C Eubanks, G Ayoub - Neuronal Signaling, 2022 - portlandpress.com
Cannabinoid and glutamatergic signaling systems in the human retina coexist and greatly
influence one another. Under glaucomatous conditions, excess levels of glutamate accrete …

Better preventing and mitigating the effects of Covid-19

G Maguire - Future Science OA, 2020 - Taylor & Francis
Currently, there are no proven medical treatments against SARS-CoV-2, the virus
responsible for Covid-19. In addition to the all important public health measures needed to …

Stem cells part of the innate and adaptive immune systems as a therapeutic for Covid-19

G Maguire - Communicative & Integrative Biology, 2021 - Taylor & Francis
Some stem cell types not only release molecules that reduce viral replication, but also
reduce the hypercytokinemia and inflammation induced by the immune system, and have …