Molecular and cellular mechanisms underlying the pathogenesis of Alzheimer's disease
Alzheimer's disease (AD) is the most common neurodegenerative disorder seen in age-
dependent dementia. There is currently no effective treatment for AD, which may be …
dependent dementia. There is currently no effective treatment for AD, which may be …
A review on recent approaches on molecular docking studies of novel compounds targeting acetylcholinesterase in Alzheimer disease
SC Peitzika, E Pontiki - Molecules, 2023 - mdpi.com
Alzheimer's disease (AD), a neurodegenerative brain disorder that affects millions of people
worldwide, is characterized by memory loss and cognitive decline. Low levels of …
worldwide, is characterized by memory loss and cognitive decline. Low levels of …
Promoted CD4+ T cell-derived IFN-γ/IL-10 by photobiomodulation therapy modulates neurogenesis to ameliorate cognitive deficits in APP/PS1 and 3xTg-AD mice
X Wu, Q Shen, H Chang, J Li, D Xing - Journal of Neuroinflammation, 2022 - Springer
Background The immune system has been implicated in synaptic plasticity, inflammation,
and the progression of Alzheimer's disease (AD). However, there were few studies on …
and the progression of Alzheimer's disease (AD). However, there were few studies on …
Neuropeptides: Potential neuroprotective agents in ischemic injury
Aim Ischemic damage to the brain is linked to an increased rate of morbidity and mortality
worldwide. In certain parts of the world, it remains a leading cause of mortality and the …
worldwide. In certain parts of the world, it remains a leading cause of mortality and the …
Hearing loss and cognitive impairment: epidemiology, common pathophysiological findings, and treatment considerations
A Bisogno, A Scarpa, S Di Girolamo, P De Luca… - Life, 2021 - mdpi.com
In recent years, there has been increasing research interest in the correlation between
hearing impairment and cognitive decline, two conditions that have demonstrated a strong …
hearing impairment and cognitive decline, two conditions that have demonstrated a strong …
Dysregulation of neuropeptide and tau peptide signatures in human Alzheimer's disease brain
S Podvin, Z Jiang, B Boyarko, LA Rossitto… - ACS Chemical …, 2022 - ACS Publications
Synaptic dysfunction and loss occur in Alzheimer's disease (AD) brains, which results in
cognitive deficits and brain neurodegeneration. Neuropeptides comprise the major group of …
cognitive deficits and brain neurodegeneration. Neuropeptides comprise the major group of …
Noise as a cause of neurodegenerative disorders: molecular and cellular mechanisms
AL Manukyan - Neurological Sciences, 2022 - Springer
Noise as an environmental stressor becomes of increasing importance in our industrialized
world, and especially traffic noise from the environment represents a potential novel …
world, and especially traffic noise from the environment represents a potential novel …
Cholecystokinin octapeptide improves hippocampal glutamatergic synaptogenesis and postoperative cognition by inhibiting induction of A1 reactive astrocytes in …
L Chen, N Yang, Y Li, Y Li, J Hong… - CNS Neuroscience …, 2021 - Wiley Online Library
Aims Delayed neurocognitive recovery (dNCR) is a common postoperative complication in
geriatric surgical patients for which there is no efficacious therapy. Cholecystokinin …
geriatric surgical patients for which there is no efficacious therapy. Cholecystokinin …
Nutraceuticals-based therapeutic approach: Recent advances to combat pathogenesis of Alzheimer's disease
Introduction: Alzheimer's disease (AD) is a progressive neurodegenerative disease
accompanying memory deficits. The available pharmaceutical care has some limitations …
accompanying memory deficits. The available pharmaceutical care has some limitations …
Identification of hub genes associated with cognition in the hippocampus of Alzheimer's Disease
YJ Liu, TT Liu, LH Jiang, Q Liu, ZL Ma, TJ Xia… - …, 2021 - Taylor & Francis
Alzheimer's Disease (AD) is a neurodegenerative disease featured by cognitive impairment.
This bioinformatic analysis was used to identify hub genes related to cognitive dysfunction in …
This bioinformatic analysis was used to identify hub genes related to cognitive dysfunction in …