Objective Juvenile‐onset fibromyalgia (JFM) is a paradigmatic chronic pain condition for
which the underlying neurobiological substrates are poorly understood. This study …

Sex differences are a robust finding in many areas of adult health, including cardiovascular
disease, psychiatric disorders, and chronic pain. However, many sex differences are not …

Classically, pain can be of a nociceptive or neuropathic nature, which refers to non-neural or
neural tissue lesions, respectively. Chronic pain in conditions such as migraine …

Juvenile fibromyalgia (JFM) is a chronic widespread pain condition that primarily affects
adolescent girls. Previous studies have found increased sensitivity to noxious pressure in …

Objective Fibromyalgia (FM) is a chronic pain disorder that takes a severe physical and
psychological toll on patients and severely reduces their quality of life. In recent years, an …

Gray matter (GM) changes are often observed in people with chronic spinal pain, including
those with chronic whiplash-associated disorders (CWAD). These GM adaptations may be …

Objective Juvenile fibromyalgia (JFM) is a chronic pain syndrome predominantly affecting
adolescent girls. Resilience may be a protective factor in coping with pain, reducing affective …

Background Fibromyalgia (FM), involving somatic, cognitive, and affective domains is often
regarded as a hallmark central sensitization syndrome. Despite limited current therapeutic …

Juvenile fibromyalgia (JFM) is a poorly understood chronic pain condition that
predominantly affects female adolescents. It is characterized by persistent widespread …

Esta tese apresenta o desenvolvimento de novas metodologias analíticas que combinam as
leituras instrumentais da espectrometria de massas com classificação multivariada, na …