Latest developments in coumarin-based anticancer agents: mechanism of action and structure–activity relationship studies

M Koley, J Han, VA Soloshonok… - RSC Medicinal …, 2023 - pmc.ncbi.nlm.nih.gov
Many researchers around the world are working on the development of novel anticancer
drugs with different mechanisms of action. In this case, coumarin is a highly promising …

Cold Kit Labeling: The Future of 68Ga Radiopharmaceuticals?

N Lepareur - Frontiers in Medicine, 2022 - frontiersin.org
Over the last couple of decades, gallium-68 (68Ga) has gained a formidable interest for PET
molecular imaging of various conditions, from cancer to infection, through cardiac …

Inductively Coupled Plasma-Mass Spectrometry (ICP-MS): An Emerging Tool in Radiopharmaceutical Science

KD Klika, J Han, MS Busse… - Journal of the …, 2024 - ACS Publications
Although radioactive experiments are necessary in radiopharmaceutical drug discovery and
theranostic cancer research, they are expensive, require special facilities, and face certain …

Modern developments in bifunctional chelator design for gallium radiopharmaceuticals

PRWJ Davey, BM Paterson - Molecules, 2022 - mdpi.com
The positron-emitting radionuclide gallium-68 has become increasingly utilised in both
preclinical and clinical settings with positron emission tomography (PET). The synthesis of …

Hydrothermally synthesized tannic acid-copper (I) complex-based nanoparticles for efficient decontamination of lead ions from aqueous solutions

A Makarem, M Gheibi, R Mirsafaei… - Journal of Molecular …, 2023 - Elsevier
In this work, we synthesized a novel wrinkled carbon-Cu 2 O nanoparticle adsorbent
(namely HWC-Cu 2 O NPs) through a hydrothermal method using tannic acid (TA) and Cu …

Radiolabeled carbon-based nanostructures: New radiopharmaceuticals for cancer therapy?

M Jaymand, YD Taghipour, A Rezaei… - Coordination Chemistry …, 2021 - Elsevier
Nanomaterials are sophisticated multifunctional structures, with the potential to improve the
efficacy of conventional cancer treatment modalities. The combination of nanomaterials with …

One‐step hydrothermal synthesis of a green NiCo‐LDHs‐rGO composite for the treatment of lead ion in aqueous solutions

A Makarem, A Aldaghi, M Gheibi… - … Canadian Journal of …, 2024 - Wiley Online Library
Herein, we have synthesized a microspherical nickel‐cobalt‐layered double hydroxides‐
reduced graphene oxide composite (NiCo‐LDHs‐rGO) through a one‐step hydrothermal …

Synthesis of a polyaminocarboxylate-based aluminum complex and its structural studies using 1 H {13 C}-HMBC NMR and a Karplus-type function

KD Klika, R Alsalim, M Eftekhari, A Makarem - Dalton Transactions, 2022 - pubs.rsc.org
The HBED chelator is used to stabilize small and hard metal ions such as Fe3+, Ti4+, Ga3+
and Al3+ in both medicine and industry. While the coordination of hexadentate HBED4− is …

Recent advances in the multicomponent synthesis of heterocycles using 5-aminotetrazole

R Javahershenas, H Mei, M Koley, VA Soloshonok… - …, 2024 - thieme-connect.com
The unique reactivity and beneficial features of the 5-aminotetrazole synthon (1H-tetrazol-5-
amine) have made it a versatile and effective building block in the synthesis of heterocyclic …

Synthesis and ex vivo biodistribution of two 68Ga-labeled tetrazine tracers: comparison of pharmacokinetics

E Lambidis, D Lumén, E Koskipahta… - Nuclear Medicine and …, 2022 - Elsevier
Pretargeted PET imaging allows the use of radiotracers labeled with short-living PET
radionuclides for tracing drugs with slow pharmacokinetics. Recently, especially methods …