Objective: To empirically derive the optimal measure of pharmacologic cardiovascular
support in infants undergoing cardiac surgery with bypass and to assess the association …

Cardiopulmonary bypass (CPB) facilitates the repair of cardiac lesions in adults and
children. Surgical mortality has decreased with improvements in technique allowing for the …

Background: Corticosteroids have been administered prophylactically for more than 60
years in pediatric heart surgery, however, their use remains a matter of debate. There are …

Cardiopulmonary bypass (CPB) is required during most cardiac surgeries. CBP drives
systemic inflammation and multiorgan dysfunction that is especially severe in neonatal …

Background: The efficacy of intraoperative corticosteroids to improve outcomes following
congenital cardiac operations remains controversial. Objectives: The purpose of this study …

Surgery and anesthesia induce inflammatory changes in the central nervous system, which
ultimately lead to neuronal damage concomitant with an increase in the level of …

The potential role of systemic inflammation on brain injury in newborns with congenital heart
disease (CHD) was assessed by measuring levels of central nervous system (CNS)‑derived …

For decades, physicians have administered corticosteroids in the perioperative period to
infants undergoing heart surgery with cardiopulmonary bypass (CPB) to reduce the …

Objective: Data supporting the use of perioperative steroids during cardiac surgery are
conflicting, and most pediatric studies have been limited by small sample sizes and/or …

Objectives: To examine the association between cardiopulmonary bypass–related systemic
inflammation and resting energy expenditure in pediatric subjects following cardiac surgery …