Abstract Arachidonic acid 15-lipoxygenase (ALOX15) is an enzyme that can oxidize
polyunsaturated fatty acids. ALOX15 is strongly expressed in airway epithelial cells, where it …

Oxo-6, 8, 11, 14-eicosatetraenoic acid (5-oxo-ETE) is an arachidonic acid metabolite formed
by oxidation of the 5-lipoxygenase (5-LO) product 5S-hydroxy-6, 8, 11, 14-eicosatetraenoic …

Sponges contain an astounding diversity of lipids that serve in several biological functions,
including yolk formation in their oocytes and embryos. The study of lipid metabolism during …

Exposure to air pollution and other environmental inhalation hazards, such as occupational
exposures to dusts and fumes, aeroallergens, and tobacco smoke, is a significant cause of …

Background: Asthma is a chronic lung disease characterized by reversible airflow
obstruction, airway hyperresponsiveness (AHR), mucus overproduction and inflammation …

Background: 5-Oxo-6, 8, 11, 14-eicosatetraenoic acid (5-Oxo-ETE) is a metabolite of
arachidonic acid shown to promote biological activities in different cell types. Summary: 5 …

Abstract Leukotriene B 4 (LTB 4) is a lipid mediator of inflammation that is generated from
arachidonic acid via the 5-lipoxygenase pathway. Previous studies have reported that the …

Allergic rhinitis (AR) is one of the most common allergic inflammatory diseases worldwide. In
AR, increased blood flow and vascular permeability in nasal mucosa cause rhinorrhea and …

Asthma is one of the most common noncommunicable diseases in the world. Approximately
30% of severe cases are associated with fungal sensitization, often associated with allergy …

目的探讨维生素A 联合糖皮质激素对哮喘小鼠气道上皮的结构和功能的影响. 方法将6~ 8 周SPF
级C57bl/6 雌性小鼠按随机数字表法分为5 组: 对照组, 哮喘组(asthma), 地塞米松组(Dex) …