[HTML][HTML] Metagenomic data assembly–the way of decoding unknown microorganisms

AL Lapidus, AI Korobeynikov - Frontiers in Microbiology, 2021 - frontiersin.org
Metagenomics is a segment of conventional microbial genomics dedicated to the
sequencing and analysis of combined genomic DNA of entire environmental samples. The …

New approaches for metagenome assembly with short reads

M Ayling, MD Clark, RM Leggett - Briefings in bioinformatics, 2020 - academic.oup.com
In recent years, the use of longer range read data combined with advances in assembly
algorithms has stimulated big improvements in the contiguity and quality of genome …

[HTML][HTML] Bacteriophage targeting microbiota alleviates non-alcoholic fatty liver disease induced by high alcohol-producing Klebsiella pneumoniae

L Gan, Y Feng, B Du, H Fu, Z Tian, G Xue… - Nature …, 2023 - nature.com
Our previous studies have shown that high alcohol-producing Klebsiella pneumoniae (HiAlc
Kpn) in the intestinal microbiome could be one of the causes of non-alcoholic fatty liver …

Healthy human gut phageome

P Manrique, B Bolduc, ST Walk… - Proceedings of the …, 2016 - National Acad Sciences
The role of bacteriophages in influencing the structure and function of the healthy human gut
microbiome is unknown. With few exceptions, previous studies have found a high level of …

Assembling large genomes with single-molecule sequencing and locality-sensitive hashing

K Berlin, S Koren, CS Chin, JP Drake… - Nature …, 2015 - nature.com
Long-read, single-molecule real-time (SMRT) sequencing is routinely used to finish
microbial genomes, but available assembly methods have not scaled well to larger …

[HTML][HTML] Extremely high mutation rate of HIV-1 in vivo

JM Cuevas, R Geller, R Garijo, J López-Aldeguer… - PLoS …, 2015 - journals.plos.org
Rates of spontaneous mutation critically determine the genetic diversity and evolution of
RNA viruses. Although these rates have been characterized in vitro and in cell culture …

SARS‐CoV‐2 spike mRNA vaccine sequences circulate in blood up to 28 days after COVID‐19 vaccination

JAS Castruita, UV Schneider, S Mollerup… - Apmis, 2023 - Wiley Online Library
In Denmark, vaccination against Severe Acute Respiratory Syndrome Corona Virus 2 (SARS‐
CoV‐2) has been with the Pfizer‐BioNTech (BTN162b2) or the Moderna (mRNA‐1273) …

[HTML][HTML] An introduction to next generation sequencing bioinformatic analysis in gut microbiome studies

B Gao, L Chi, Y Zhu, X Shi, P Tu, B Li, J Yin, N Gao… - Biomolecules, 2021 - mdpi.com
The gut microbiome is a microbial ecosystem which expresses 100 times more genes than
the human host and plays an essential role in human health and disease pathogenesis …

Characterization of a novel orthomyxo-like virus causing mass die-offs of tilapia

E Bacharach, N Mishra, T Briese, MC Zody… - MBio, 2016 - Am Soc Microbiol
Tilapia are an important global food source due to their omnivorous diet, tolerance for high-
density aquaculture, and relative disease resistance. Since 2009, tilapia aquaculture has …

Elevated virulence of an emerging viral genotype as a driver of honeybee loss

DP McMahon, ME Natsopoulou… - … of the Royal …, 2016 - royalsocietypublishing.org
Emerging infectious diseases (EIDs) have contributed significantly to the current biodiversity
crisis, leading to widespread epidemics and population loss. Owing to genetic variation in …