BTB domains: a structural view of evolution, multimerization, and protein–protein interactions

A Bonchuk, K Balagurov, P Georgiev - Bioessays, 2023 - Wiley Online Library
Abstract Broad‐complex, Tramtrack, and Bric‐à‐brac/poxvirus and zinc finger (BTB/POZ) is
a conserved domain found in many eukaryotic proteins with diverse cellular functions …

Distinct structural bases for sequence-specific DNA binding by mammalian BEN domain proteins

L Zheng, J Liu, L Niu, M Kamran… - Genes & …, 2022 - genesdev.cshlp.org
The BEN domain is a recently recognized DNA binding module that is present in diverse
metazoans and certain viruses. Several BEN domain factors are known as transcriptional …

Identification and characterization of BEND2 as a key regulator of meiosis during mouse spermatogenesis

L Ma, D Xie, M Luo, X Lin, H Nie, J Chen, C Gao… - Science …, 2022 - science.org
The chromatin state, which undergoes global changes during spermatogenesis, is critical to
meiotic initiation and progression. However, the key regulators involved and the underlying …

Nacc1 mutation in mice models rare neurodevelopmental disorder with underlying synaptic dysfunction

MA Deehan, JM Kothuis, E Sapp, K Chase… - Journal of …, 2024 - Soc Neuroscience
A missense mutation in the transcription repressor Nucleus accumbens-associated 1
(NACC1) gene at c. 892C> T (p. Arg298Trp) on chromosome 19 causes severe …

Interaction mechanism of collagen peptides with four phenolic compounds in the ethanol-water solution

X Liu, X Li, Z Huang, X Liao, B Shi - Journal of Leather Science and …, 2021 - Springer
This study demonstrated the interaction mechanism of collagen peptides (CPs) with 4-
ethylphenol (4-EP), phenol, guaiacol, and 4-ethylguaiacol (4-EG) in the ethanol-water …

DNA-binding proteins from MBD through ZF to BEN: recognition of cytosine methylation status by one arginine with two conformations

X Zhang, RM Blumenthal, X Cheng - Nucleic Acids Research, 2024 - academic.oup.com
Maintenance methylation, of palindromic CpG dinucleotides at DNA replication forks, is
crucial for the faithful mitotic inheritance of genomic 5-methylcytosine (5mC) methylation …

[HTML][HTML] Nucleus Accumbens Associated Protein 1 in Cancers—The Real Value

M Janiczek-Polewska, T Kolenda, P Poter… - International Journal of …, 2024 - mdpi.com
Malignant tumors are a leading cause of death worldwide, second only to cardiovascular
disease. They occur in every population and have a high risk of mortality. The …

A New Case of de novo Variant c.892C>T (p.Arg298Trp) in NACC1: A First Case Report From China

B Lyu, Y Dong, J Kang - Frontiers in Pediatrics, 2021 - frontiersin.org
Background: The nucleus accumbens associated 1 (NACC1) gene is a transcription factor
member of the BTB/POZ family. A de novo heterozygous c. 892C> T (p. Arg298Trp) variant …

Soft‐tissue sarcoma with MN1‐BEND2 fusion: A case report and comparison with astroblastoma

A Yoshida, K Satomi, E Kobayashi… - Genes …, 2022 - Wiley Online Library
MN1‐BEND2 is considered as a defining gene fusion of astroblastoma. Herein, we report
the first case of soft‐tissue sarcoma with this fusion. The tumor developed in the abdominal …

The Critical Role of NAC1 in Triple-Negative Breast Cancer Stemness and Immunosuppression

C Ngule - 2024 - search.proquest.com
Triple-negative breast cancer (TNBC) is a highly heterogeneous and the most lethal breast
cancer (BC) subtype. We report here a new role of nucleus accumbens associated protein 1 …